Adult 1 g 8 hrly or 2 g 12 hrly. Severe infection 2 g 8 or 12 hrly. Infant & childn >2 mth 30-100 mg/kg daily in 2-3 divided doses. Max: 6 g daily. Neonate & childn ≤2 mth 25-60 mg/kg daily in 2 divided doses. Elderly >80 yr Max: 3 g daily.
Hypersensitivity to cephalosporins.
Hypersensitivity to penicillins. Pregnancy & lactation.
Thrombophlebitis (IV route), local pain &/or inflammation (IM route), GI upset, CNS effect. Rarely, hypersensitivity reactions & transient haematological changes.