Vaxcel Lignocaine 1%

Vaxcel Lignocaine 1%

lidocaine

Manufacturer:

Kotra Pharma

Distributor:

Kotra Pharma
Concise Prescribing Info
Contents
Lignocaine HCl
Indications/Uses
Local or regional anaesth, peripheral nerve block, infiltration anaesth & diagnostic or therapeutic block.
Dosage/Direction for Use
Adult Infiltration Percutaneous: 5-300 mg. Peripheral nerve block Brachial: 225-300 mg. Intercostal: 30 mg. Paracervical: 100 mg/side as 1% soln, may be repeated at intervals of not <90 min. Paravertebral: 30-50 mg. Retrobulbar: 120-200 mg. Sympathetic nerve block Cervical: 50 mg. Transtracheal: 80-120 mg & additional 4% spray to pharynx may be required. Max: Not to exceed 4.5 mg/kg. Childn Local infiltration Up to 4.5 mg/kg as 0.25-5% soln. Nerve block Up to 4.5 mg/kg as 0.5-1% soln.
Contraindications
Hypersensitivity to lignocaine HCl or local anaesth of amide type. Uncorrected hypotension or coagulation disorder or patients receiving anticoagulants. Inflammation or sepsis in region of proposed inj; septicaemia.
Special Precautions
Insert IV cannula prior to anaesth inj. Avoid inadvertent intravascular inj. Constant monitoring of CV & resp vital signs. Impaired CV functions, hypovolemia, CHF, bradycardia, shock & complete heart block. Epilepsy, impaired cardiac conduction & resp function, myasthenia gravis. Hepatic & renal impairment. Cerebrospinal diseases, altered coagulation status. Not to be inj to inflamed or infected tissues, damage skin or mucosa. Hepatic or renal impairment. Pregnancy & lactation. Childn. Elderly.
Adverse Reactions
Raised plasma conc. Restlessness, excitement, nervousness, dizziness, tinnitus, blurred vision, nausea & vomiting, muscle twitching, tremors & convulsions. Tongue & perioral region numbness. Transient excitation, depression w/ drowsiness, resp failure & coma. Myocardial depression & peripheral vasodilation resulting in hypotension & bradycardia, arrhythmias & cardiac arrest. Methaemoglobinaemia. Fetal intoxication. Maternal hypotension. Allergic reactions eg, cutaneous lesions, urticaria, oedema.
Drug Interactions
Increased risk of myocardial depression w/ antiarrhythmics eg, bupivacaine, levobupivacaine, ropivacaine. Reduced clearance by propranolol & cimetidine. Additive cardiac depressant effects w/ β-blockers, IV phenytoin & other antiarrhythmics. Excessive neuromuscular blockage w/ skeletal muscle relaxants eg, suxamethonium. Structurally-related local anaesth.
MIMS Class
Anaesthetics - Local & General
ATC Classification
N01BB02 - lidocaine ; Belongs to the class of amides. Used as local anesthetics.
Presentation/Packing
Form
Vaxcel Lignocaine 1% soln for inj 10 mg/mL
Packing/Price
5 mL x 10 × 1's
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