Pre-exposure 3 IM inj on D0, D7 & D28 followed by booster dose after 1 yr & subsequent booster dose every 5 yr. Fully immunized patient 2 booster doses on D0 & D3. Non-immunized patient 5 IM inj on D0, D3, D7, D14 & D28. May be used w/ human rabies Ig 20 IU/kg or equine rabies Ig 40 IU/kg.
View Verorab overdosage for action to be taken in the event of an overdose.
Contraindications
Not to be inj intradermally in immunocompromised individuals, w/ concomitant long-term corticosteroids, immunosuppresives or chloroquine, w/ severe wounds. Pre-exposure: Hypersensitivity to rabies virus, polymyxin B, streptomycin, neomycin or previous inj. Postpone vaccination in case of febrile or acute diseases.
Known hypersensitivity to polymyxin B, streptomycin, neomycin. Not to be inj intravascularly or into gluteal area. Known immunodeficiency due to immunosuppressive illness or concomitant immunosuppressive treatment eg, corticosteroids. Thrombocytopenia, coagulation disorders. Anxiety-related reactions eg, syncope, hyperventilation or stress-related reactions. May affect ability to drive & use machines. Pregnancy. Premature infants ≤28 gestation wk & w/ history of resp immaturity.
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