vaccine, rabies


sanofi pasteur


Zuellig Pharma
Concise Prescribing Info
Purified inactivated rabies vaccine (Wistar rabies PM/WI 38 1503-3M strain) prepared on Vero cells
Prevention of rabies in childn & adult. Primary vaccination or booster dose before & after exposure.
Dosage/Direction for Use
Pre-exposure 3 IM inj on D0, D7 & D28 followed by booster dose after 1 yr & subsequent booster dose every 5 yr. Fully immunized patient 2 booster doses on D0 & D3. Non-immunized patient 5 IM inj on D0, D3, D7, D14 & D28. May be used w/ human rabies Ig 20 IU/kg or equine rabies Ig 40 IU/kg.
Not to be inj intradermally in immunocompromised individuals, w/ concomitant long-term corticosteroids, immunosuppresives or chloroquine, w/ severe wounds. Pre-exposure: Hypersensitivity to rabies virus, polymyxin B, streptomycin, neomycin or previous inj. Postpone vaccination in case of febrile or acute diseases.
Special Precautions
Known hypersensitivity to polymyxin B, streptomycin, neomycin. Not to be inj intravascularly or into gluteal area. Known immunodeficiency due to immunosuppressive illness or concomitant immunosuppressive treatment eg, corticosteroids. Thrombocytopenia, coagulation disorders. Anxiety-related reactions eg, syncope, hyperventilation or stress-related reactions. May affect ability to drive & use machines. Pregnancy. Premature infants ≤28 gestation wk & w/ history of resp immaturity.
Adverse Reactions
Adenopathy/lymphadenopathy; myalgia; inj site pain, fever, malaise. Cutaneous allergic reactions eg, rash, pruritus, oedema; headache, dizziness, somnolence; abdominal pain, nausea; arthralgia, shivering; inj site erythema, pruritus, haematoma & induration, asthenia, flu-like syndrome.
Drug Interactions
Interfered Ab production w/ corticosteroids & immunosuppressives. Not to be administered at same site w/ rabies Ig.
MIMS Class
Vaccines, Antisera & Immunologicals
ATC Classification
J07BG01 - rabies, inactivated, whole virus ; Belongs to the class of rabies viral vaccines.
Verorab vaccine (inj)
0.5 mL x 1's
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