Each mL of VIGAMOX Solution contains 5.45 mg moxifloxacin hydrochloride equivalent to 5 mg moxifloxacin base.
Contains: Active: Moxifloxacin 0.5% (5 mg/mL); Preservative: None. Product is self-preserved.
VIGAMOX (moxifloxacin HCl ophthalmic solution) 0.5% is a sterile topical ophthalmic solution.
Moxifloxacin is a fourth-generation fluoroquinolone antibacterial agent active against a broad spectrum of Gram-positive and Gram-negative ocular pathogens, atypical microorganisms and anaerobes.
Chemical Name: 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolol[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid, monohydrochloride. Moxifloxacin differs from other quinolones in that it has a methoxy function at the 8 position, and an S,S-configured diazabicyclononyl ring moiety at the 7-position.
Moxifloxacin hydrochloride is a slightly yellow to yellow crystalline powder.
Excipients/Inactive Ingredients: sodium chloride, boric acid and purified water. May also contain hydrochloric acid/sodium hydroxide to adjust pH. VIGAMOX Solution is isotonic and formulated at pH 6.8 with an osmolality of approximately 290 mOsm/kg.