Vinorelbine is used on its own or together with other medicines to treat certain types of cancer of the lungs and breast.
Vinorelbine is to be given intravenously (into the vein) via infusion (drip). It is delivered into the bloodstream via the blood vessel.
Your doctor or nurse will administer the injection for you.
The dose of this medicine will be decided by your doctor. Your doctor will advise you on the course of the treatment depending on your condition and response to the medication.
Ensure that you keep all appointments with your doctor so that you do not miss any dose. Your doctor also needs to regularly monitor your response to Vinorelbine.
If you miss an appointment or miss an injection with your doctor, alert your doctor or nurse. A replacement appointment or infusion should be given as soon as possible.
Alert your doctor if you have the following conditions:
- severe liver disease
- low white blood cell count or a severe infection
- low platelet count
as Vinorelbine may not be suitable for you.
DO NOT use this medicine if you are pregnant. If you become pregnant while on Vinorelbine therapy, alert your doctor immediately. This medicine may cause harm to your unborn child.
Men should not father a child while being treated with this medicine. Both men and women must use proven birth control methods during Vinorelbine therapy and for 3 months after stopping the treatment. You may wish to discuss other reliable methods of birth control with your doctor.
DO NOT breastfeed while you are being treated with this medicine.
Alert your doctor if you have been recently vaccinated. You must avoid any vaccinations without first consulting your doctor.
Inform your doctor if you have the following conditions:
- liver disease
- heart disease e.g. chest pain, heart attack
Why is it important to keep my appointments with the doctor?
Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
- Pregnancy tests must be done before the treatment initiation to know if this medicine is suited for you to use.
- Routine tests (blood count, liver function test) may be done while you are being treated with this medicine. Your doctor will advise you about how often you will need to have these tests.
Vinorelbine may cause dizziness and fatigue. If affected, do not drive or take part in any activity in which you need to be alert.
Other side effects include any of the following: nausea, vomiting, diarrhoea, mouth sore, hair loss, pain in the joint, jaw or muscle, and injection site reaction e.g. redness, pain.
This medicine may cause the level of your red blood cells, white blood cells and platelets to drop.
Red blood cells carry oxygen around your body. A fall in the level of red blood cells may make you feel tired and worn out.
White blood cells help your body to fight infections. A fall in the level of your white blood cells may put you at higher risk for infections, such as coughs, colds and flu, which may lead to more serious infections. Avoid crowded places and people who are sick. Inform your doctor if you have a fever or a cough or flu that does not go away.
Platelets help your blood to clot when there is a cut in the skin. A fall in the level of your platelets may put you at risk of bleeding more than usual. Do not take part in activities where you may fall or get injured, such as contact sports. Inform your doctor if you get any unusual bruising (large bruises or several bruises, especially if the bruises appeared on their own) or bleeding that takes a long time to stop (for example, too much bleeding when you floss or brush your teeth).
Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
- rashes, breathlessness, swelling of the face, eyes or mouth
- severe constipation, stomach pain
- severe chest pain
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Inform your doctor and pharmacist if you are taking any of these medicines:
- blood-thinning medicine e.g. warfarin, phenindione
- medicines used to treat fungal infection e.g. itraconazole, ketoconazole
- phenytoin (medicine for epilepsy)
- ritonavir (medicine used for HIV infections)
- rifampicin (medicine used for an infection known as tuberculosis)
- medicines used in organ transplant or certain immune disorders e.g. ciclosporin, tacrolimus
- other medicines that are used to treat cancer e.g. mitomycin, cisplatin, lapatinib
This list does not include all medicines that may interact with Vinorelbine.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
Store in the refrigerator, between 2-8°C. Do not allow to freeze. If frozen, this medicine will become ineffective and should not be used.
Protect from light.
As this is a cancer medicine, always return any unused or expired medicine to the clinic, hospital, or pharmacy for disposal.