Vivocin

Vivocin

vancomycin

Manufacturer:

Gland Pharma

Distributor:

Unimed
Concise Prescribing Info
Contents
Vancomycin HCl
Indications/Uses
Serious or severe infections caused by susceptible strains of methicillin-resistant (β-lactam-resistant) staphylococci in penicillin-allergic patients & who cannot receive or have failed to respond to penicillins or cephalosporins. Infections caused by vancomycin-susceptible organisms resistant to other antimicrobial drugs.
Dosage/Direction for Use
Adult 2 g divided as 500 mg every 6 hr or 1 g every 12 hr administered at no >10 mg/min over at least 60 min. Ped 10 mg/kg/dose every 6 hr administered over at least 60 min. Neonate Initially 15 mg/kg followed by 10 mg/kg every 12 hr for neonate in 1st wk of life & every 8 hr thereafter up to 1 mth administered over 60 min. Mild to moderate renal insufficiency & anephric patient Initially no <15 mg/kg. Maintenance dose: 1.9 mg/kg/24 hr. Marked renal impairment Maintenance dose: 250-1,000 mg once every several days. Anuria 1,000 mg every 7-10 days.
Contraindications
Special Precautions
Hypersensitivity. Allergic reactions to teicoplanin. Acute anuria or cochlear damage. Rapid bolus administration. Not to be used as intraperitonial, IM inj. Nephrotoxicity; ototoxicity, prior deafness. Superinfections; pseudomembranous colitis. Monitor leukocyte count. Periodically determine blood levels, auditory function, haematologic studies, urine analysis, hepatic & renal function tests. Prolonged use. Concomitant use w/ other ototoxic drugs eg, aminoglycoside, anesth, neutropenia- or agranulocytosis-causing drugs. Renal failure. Pregnancy & lactation. Premature infants & childn. Elderly >60 yr.
Adverse Reactions
Phlebitis, pseudo-allergic reactions. Decreased BP, thrombophlebitis; dyspnoea, stridor; exanthema, mucosal inflammation, pruritus, urticaria; renal insufficiency; upper body & face redness, chest & back muscles pain & spasms.
Drug Interactions
Potentiated nephrotoxicity &/or ototoxicity w/ other potentially neurotoxic &/or nephrotoxic active substances particularly gentamycin, amphotericin B, streptomycin, neomycin, kanamycin, amikacin, tobramycin, viomycin, bacitracin, polymyxin B, colistin, cisplatin. Anaphylactoid reactions w/ anesth agents. Enhanced & prolonged effect of muscle relaxants eg, succinylcholine. Physical incompatibilities w/ β-lactam soln.
MIMS Class
Other Antibiotics
ATC Classification
J01XA01 - vancomycin ; Belongs to the class of glycopeptide antibacterials. Used in the systemic treatment of infections.
Presentation/Packing
Form
Vivocin powd for inj 500 mg
Packing/Price
10 mL x 10 × 1's
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