Discontinue use in organ transplant patients. Patients w/ NYHA class IV. Monitor for increase in LFTs & decrease in thyroxine levels. Concomitant use w/ sorbitol- or fructose-containing medicinal products. Severe hepatic & renal impairment. Women of childbearing potential should use effective contraception during & for 1 mth after last dose. Not recommended during pregnancy. Not to be used during lactation. Childn.