Each vial contains 120 mg denosumab in 1.7 mL solution (70 mg/mL).
Denosumab is a human monoclonal IgG2 antibody produced in a mammalian cell line (Chinese hamster ovary cells) by recombinant DNA technology.
Excipient with known effects: Each 1.7 mL of solution contains 78 mg sorbitol (E420).
Excipients/Inactive Ingredients: Sorbitol, Glacial acetic acid*, Sodium hydroxide, Water for Injection.
*Acetate buffer is formed by mixing acetic acid with sodium hydroxide.