Hypersensitivity; nasal polyps, angioedema & bronchospastic reactivity to aspirin & other NSAIDs. History of & other risk factors associated w/ PUD, history of serious GI events, smoking, alcoholism, CV disease or risk of an adverse CV event, HTN, intrinsic coagulation defects, non-infectious non-inflammatory painful conditions. Patients on anticoagulant therapy. Hepatic & renal impairment. Avoid use during late pregnancy. Not recommended for childn <1 yr or <7 kg. Elderly.