Zevin

Zevin

aciclovir

Manufacturer:

Biolab

Distributor:

Medispec
Concise Prescribing Info
Contents
Acyclovir
Indications/Uses
Herpes simplex virus, varicella & herpes zoster infections. Suppression & prophylaxis of herpes simplex infections in immune-compromised patients.
Dosage/Direction for Use
Adult Herpes simplex 200 mg 5 times daily for 5 days. Severely immunocompromised patient 400 mg 5 times daily for 5 days. Suppression of herpes simplex 200 mg qds or 400 mg bd, interrupted periodically at 6-12 mth intervals. Prophylaxis of herpes simplex 200 mg qds. Severely immunocompromised patient 400 mg qds. Herpes zoster & varicella 800 mg 5 times daily for 7 days. Treatment & prophylaxis of herpes simplex Childn ≥2 yr Adult dose, <2 yr ½ adult dose. Varicella infections Childn >6 yr 800 mg qds for 5 days, 2-6 yr 400 mg qds for 5 days, <2 yr 200 mg qds for 5 days. Severe renal impairment Herpes simplex 200 mg bd at approx 12 hrly interval. Herpes zoster & varicella 800 mg bd at approx 12 hrly interval. Moderate renal impairment Herpes zoster & varicella 800 mg tds at approx 8 hrly interval.
Contraindications
Special Precautions
Ensure adequate hydration. Renal impairment. Pregnancy & lactation. Elderly.
Adverse Reactions
Headache, nausea, vomiting, diarrhea; skin rashes.
Drug Interactions
Increased mean plasma t½ & AUC w/ probenecid.
MIMS Class
ATC Classification
J05AB01 - aciclovir ; Belongs to the class of nucleosides and nucleotides excluding reverse transcriptase inhibitors. Used in the systemic treatment of viral infections.
Presentation/Packing
Form
Zevin tab 200 mg
Packing/Price
5 × 5's
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