Ziprasidone - oral

Patient Medicine Information
Why do I need this medicine?
Ziprasidone is used to treat schizophrenia (an illness that causes changes in perception, thoughts and behaviour). It helps relieve common symptoms of schizophrenia such as distorted thinking and emotional instability.

This medicine is also used on its own or together with other medicines to treat a mood disturbance called bipolar disorder.
How do I take this medicine?
Take Ziprasidone exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

This medicine should be taken together with food or immediately after a meal. Try to take it at the same time each day.

Ziprasidone must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have a heart disease (e.g. heart rhythm disorder, recent heart attack, heart failure) as Ziprasidone may not be suitable for you.

Do not take Ziprasidone with similar medicines used to treat abnormal heart rhythm. Please see the section “Can I take this with other medicines?” below for more information.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:
  • liver disease
  • kidney disease
  • dementia (a disorder affecting memory and thinking)
  • Parkinson’s disease (disorder that affects the movement of a person, causing symptoms such as tremors, muscle stiffness, slowed movement and impaired balance or walking)
  • epilepsy (fits or seizures)
Let your doctor know if you are pregnant or breastfeeding.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly. Various sets of routine tests may be done while you are being treated with Ziprasidone.
What side effects could I experience?
Ziprasidone may cause dizziness, drowsiness or some problems with your eyesight. This medicine may cause you to suddenly fall asleep during your daily activities such as eating and watching television. If affected, do not drive or take part in any activity in which you need to be alert or need to see clearly.

You may also feel dizzy when getting up from a sitting or lying down position, especially if you are taking this medicine for the very first time. This is common and should improve gradually as you get used to Ziprasidone. It will help if you get up slowly from a sitting or lying down position. If you are taking this medicine for the very first time, take the first dose of Ziprasidone at bedtime to minimise dizziness.

Ziprasidone may affect how your body adjusts to temperature changes. Avoid exposure to very cold or very hot environment while being treated with this medicine.

Other side effects include any of the following: headache, nausea, constipation, indigestion, rash, restlessness and weakness.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • signs of allergy such as breathlessness, rashes, swollen mouth or eyes
  • high fever
  • muscle stiffness
  • convulsion or seizures
  • thoughts of self-harm

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Do not take Ziprasidone if you are taking any of these medicines:
  • medicines for abnormal heart rhythm e.g. sotalol, quinidine, dofetilide
  • medicines for nausea or vomiting e.g. dolasetron, droperidol
  • medicines used to treat behaviour problems e.g. chlorpromazine, thioridazine, mesoridazine, pimozide
  • medicines used to treat malaria e.g. halofantrine, mefloquine
  • certain antibiotics e.g. gatifloxacin, moxifloxacin, sparfloxacin, pentamidine
  • medicines used in organ transplant or certain immune disorders e.g. tacrolimus
  • cholesterol-lowering medicine e.g. probucol
Inform your doctor and pharmacist if you are taking any of these medicines:
  • medicines to treat Parkinson’s disease e.g. levodopa
  • medicines to treat fungal infections e.g. ketoconazole
  • medicines used to treat epilepsy (fits or seizures) e.g. carbamazepine
This list does not include all medicines that may interact with Ziprasidone.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on ziprasidone - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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