Severe hypokalaemia w/ K-depleting diuretics. Increased risk of arrhythmias or digitalis toxicity associated w/ hypokalaemia w/ digitalis glycosides. Increased blood glucose conc w/ anti-diabetic agents eg, sulfonylurea or insulin. Increased risk of GI ulceration or haemorrhage w/ alcohol or NSAIDS. Increased/decreased effect of coumarin- or indandione-derivative anticoagulants, heparin, streptokinase or urokinase. Increased risk of developing viral disease w/ live virus vaccines or other immunizations. Decreased corticosteroid effect w/ liver enzyme-inducing drugs eg, rifampicin, ephedrine, barbiturates, phenytoin, phenobarb & primidone. Increased excretion & reduced salicylate plasma conc. Concomitant use w/ acetaminophen; aminoglutethimide; parenteral amphotericin B or carbonic anhydrase inhibitors; anabolic steroids or androgens; anticholinergics eg, atropine & related compd; TCAs; estrogen-containing OCs; folic acid; other immunosuppressant agents; INH, mexiletine; iophendylate or metrizamide; mitotane; nondepolarizing neuromuscular-blocking agents; pancuronium; K supplements; ritodrine; Na-containing medication or foods; somatrem or somatropin; streptozocin.