Zyloric

Zyloric

allopurinol

Manufacturer:

Aspen

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Allopurinol
Indications/Uses
Gout, hyperuricemia & uric acid lithiasis. Treatment of Ca oxalate/phosphate renal stones in the presence of hyperuricemia &/or hyperuricosuria.
Dosage/Direction for Use
Adult Mild conditions 2-10 mg/kg daily or 100-200 mg daily. Moderately severe 300-600 mg daily. Severe 700-900 mg daily. Childn <15 yr 10-20 mg/kg daily or 100-400 mg daily.
Administration
Should be taken with food: Take immediately after meals.
Contraindications
Acute gout. Asymptomatic hyperuricaemia.
Special Precautions
Hypersensitivity. Pregnancy.
Adverse Reactions
Acute attack of gouty arthritis in early stages of therapy. Skin reactions (discontinue immediately at 1st sign of rash). Very rarely, granulomatous hepatitis. Occasionally; thrombocytopenia, agranulocytosis, & aplastic anaemia in patients w/ impaired renal function.
Drug Interactions
Use only ¼ of the usual dose of 6-mercaptopurine or azathioprine when given concurrently. Increased plasma t½ of adenine arabinoside. Decreased effect by uricosurics & large doses of salicylates.
ATC Classification
M04AA01 - allopurinol ; Belongs to the class of preparations inhibiting uric acid production. Used in the treatment of gout.
Presentation/Packing
Form
Zyloric tab 300 mg
Packing/Price
30's (RM71.40/pack)
Form
Zyloric tab 100 mg
Packing/Price
100's (RM89.35/pack)
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