Animal reproduction studies have been performed at doses up to moderately maternally toxic dose concentrations. In these studies, no evidence of harm to the fetus due to azithromycin was found. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, Zynomax should be used during pregnancy only if clearly needed.
There are no data on secretion in breast milk. As many drugs are excreted in human milk, Zynomax should not be used in the treatment of a lactating woman unless the physician feels that the potential benefits justify the potential risks to the infant.