Discontinue use if posterior reversible encephalopathy/reversible cerebral vasoconstriction syndrome, sudden loss of vision or decreased visual acuity eg, scotoma; abdominal pain, rectal bleeding or other symptoms of ischaemic colitis occur. DM, hyperthyroidism, arterial HTN, tachycardia, cardiac arrhythmia, ischaemic heart disease. Patients w/ predisposing factors of urinary retention eg, spinal cord lesion, prostatic hyperplasia or hypertrophy, bladder outflow obstruction; at risk for hypercoagulability eg, inflammatory bowel disease. Concomitant use w/ sympathomimetics including decongestants, anorexigenic substances or psychostimulants, TCAs,
antihypertensives, alcohol & other CNS depressants, cardiac glycosides eg, digoxin or digitoxin; NSAIDs. Not to be taken by patients w/ galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. May affect ability to drive or operate machinery. Moderate renal or hepatic impairment. Not to be used during pregnancy & lactation. Elderly.
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