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Other Available Patient Medicine Information

> Busulfan - Oral

Busulfan - Intravenous - Patient Medicine Information

> Why do I need this medicine?
> How do I use this medicine?
> What should I do if I have forgotten to use this medicine?
> When should I not use this medicine?
> What should I take note of while using this medicine?
> What side effects could I experience?
> Can I use this with other medicines?
> What special dietary instructions should I follow?
> How should I store this medicine?

 
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Why do I need this medicine?

Busulfan is used to treat chronic myelogenous leukaemia (CML). It is a type of cancer where the bone marrow produces too many white blood cells, called granulocytes.

How do I use this medicine?

Busulfan is to be given intravenously (into the vein) via a drip. It is delivered directly into the bloodstream via the blood vessel.

Your doctor or nurse will administer this medicine to you.

Before the drip is started, you may be given other medicines to prevent or lessen the side effects of Busulfan. These medicines may be given as tablets or as injections.

What should I do if I have forgotten to use this medicine?

Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Busulfan.

If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.

DO NOT double a dose under any circumstances.

When should I not use this medicine?

Do not take this medicine if you don't have a definite diagnosis of CML as this medicine may not be suitable for you.

Alert your doctor if you are pregnant. Do not take Busulfan if you are pregnant or planning to have a baby soon. If you become pregnant while on Busulfan, alert your doctor immediately. This medicine may cause harm to your unborn child. Both men and women must use proven birth control methods while being treated with this medicine. You may wish to discuss birth control methods with your doctor.

What should I take note of while using this medicine?

Inform your doctor if you have a history of seizures (fits) and head injury.

Let your doctor know if you are breastfeeding.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly. For as long as you are taking this medicine, your doctor may need to perform blood tests e.g. complete blood count and platelet count, and also to make sure that your liver function is normal before you take this medicine and thereafter depending on your doctor's advice.

What side effects could I experience?

Busulfan may cause dizziness, weakness, and visual disturbances. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects include any of the following: headache, difficulty sleeping, anxiety, darkening of the skin, rash, hair loss, dry mouth, diarrhoea, nausea, vomiting, loss of appetite resulting to weight loss, and pain in the injection site.

This medicine may also cause irregular or absence of menstrual periods in women and sexual dysfunction in men. Discuss with your doctor if you are concerned about these side effects.

Some side effects may need medical help. Alert your doctor quickly if you experience any of the following:
- seizures (fits)
- fever with persistent sore throat or mouth ulcers, unusual bleeding or bruising
- sharp chest pain that is felt in the neck, shoulder, back or abdomen
- shortness of breath

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.

Can I use this with other medicines?

Inform your doctor and pharmacist if you are taking any of these medicines:

- medicines used to treat cancer e.g. thioguanine
- medicines for amoeba e.g. metronidazole
- medicines used to treat fungal infections e.g. itraconazole
- medicines used to treat epilepsy e.g. phenytoin
- paracetamol (medicine to relieve pain and reduce fever)

This list does not include all medicines that may interact with Busulfan.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics, such as traditional Chinese medicine, supplements and medicines that you buy without a prescription.

What special dietary instructions should I follow?

Avoid alcohol.

How should I store this medicine?

Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.

This information is independently developed by MIMS based on Busulfan - Intravenous and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2019 MIMS. All rights reserved. Powered by MIMS.com

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