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> Carbamazepine - Rectal

Carbamazepine - Oral - Patient Medicine Information

> Why do I need this medicine?
> How do I take this medicine?
> What should I do if I have forgotten to take this medicine?
> When should I not use this medicine?
> What should I take note of while using this medicine?
> What side effects could I experience?
> Can I take this with other medicines?
> What special dietary instructions should I follow?
> How should I store this medicine?

 
Available Brands

Other Known Brands
  • Taver    
  • Apo-Carbam    

Why do I need this medicine?

Carbamazepine is used on its own or together with other medicines to treat epilepsy (also known as fits or seizures).

Carbamazepine helps to relieve pain in a painful nerve condition that affects the face called trigeminal neuralgia. It can also help to relieve nerve pain in people with diabetes.

It is also used to treat a mood disturbance called bipolar disorder.

Carbamazepine may also be used to treat other medical conditions, as decided by your doctor.

How do I take this medicine?

Take Carbamazepine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Carbamazepine is available as a normal tablet, chewable tablet, extended-release tablet or capsule, and as a suspension (syrup).

Ask your doctor or pharmacist on how to take this medicine as certain preparations and brands may be taken differently.

The extended-release tablet or capsule may be labelled “CR”, “XR” or “ER”. Swallow it whole with a glass of water. Do not chew or crush the tablet or the capsule and its contents. For certain brands, contents of the extended-release capsule may be sprinkled over food or applesauce.

If you are taking the normal, chewable tablet or suspension (syrup), take it with meals. Shake the suspension well before taking your dose.

If you are taking the extended-release capsule, take it with or without food.

Do not switch between the different types of tablets or suspension unless advised by your doctor.

Carbamazepine must be taken regularly for it to be effective. Continue taking Carbamazepine even when you feel better. Carbamazepine is not a cure and you may need to take it long-term to keep your seizures under control. Do not stop taking Carbamazepine unless instructed by your doctor.

What should I do if I have forgotten to take this medicine?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.

When should I not use this medicine?

Alert your doctor if you have the following conditions:
  • history of bone marrow depression (a condition in which the blood cells are low)
  • history of porphyria (an inherited disorder that may cause skin or nerve problems)
as Carbamazepine may not be suitable for you.

Do not take Carbamazepine if you are currently taking or have taken a medicine to treat depression known as a monoamine oxidase inhibitor (MAOI) such as isocarboxazid, phenelzine and tranylcypromine in the last 14 days.

What should I take note of while using this medicine?

Inform your doctor if you have:
  • liver disease 
  • kidney disease 
  • heart disease
  • blood disorders as a result of taking other medicines
  • glaucoma (increased pressure in the eye)
  • urinary problems 
  • long-term constipation
  • mental illness or mood disorders
  • an allergy to other epilepsy medicines such as phenytoin or oxcarbazepine or medicines to treat depression such as amitriptyline
Let your doctor know if you are pregnant or breastfeeding.

You may see a small tablet-shaped casing in your bowel movements. This is normal; do not be alarmed. This casing is just an empty shell; the medicine inside it has already been absorbed by your body.

Some genetic traits can cause serious allergic reactions (e.g. rashes with skin peeling or blisters) from this medicine. If you have certain pairs of gene called HLA-B*15:02, HLA-A*31:01, you are more likely to develop these reactions to Carbamazepine. Your doctor may perform genetic testing before giving you this medicine. However, you may still develop skin reactions if you do not have this gene type. Please monitor for any signs of skin rashes.

For as long as you are taking Carbamazepine, you will need to have your eyes checked regularly. You may also need to have regular blood tests and urine tests. These tests help to monitor your body's response to Carbamazepine. Your doctor will advise you about how often you need to have these tests done.

If you are going for an operation, including minor operations and dental work, inform your doctor or dentist that you are taking Carbamazepine.

What side effects could I experience?

Carbamazepine may cause drowsiness, tiredness and dizziness. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects include any of the following: headache, difficulty in controlling movement such as unsteadiness in walking or involuntary eye movements, double or blurred vision, nausea, vomiting, dry mouth, diarrhoea, constipation and itch. These side effects are common especially when you have just started taking Carbamazepine.

Some side effects may be serious, although they are not common. Alert your doctor quickly if you experience:
  • rashes with peeling of the skin or blistering of the lips, mouth or eyes accompanied by fever
  • swelling of the eyes, face or lips or breathing difficulties
  • extensive or unusual bleeding or bruising
  • mouth ulcers or persistent fever or sore throat
  • yellowing of the skin or eyes with abdominal pain or persistent tiredness, nausea or vomiting
  • confusion or hallucinations (seeing or hearing things that are not existent)
  • unusual changes in mood or behaviour (being too depressed, agitated, or having thoughts of self-harm)
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.

Can I take this with other medicines?

Do not take Carbamazepine if you are currently taking or have taken a medicine to treat depression known as a MAOI such as isocarboxazid, phenelzine and tranylcypromine in the last 14 days.

Inform your doctor and pharmacist if you are taking these medicines:
  • other medicines for epilepsy e.g. valproic acid, clonazepam, phenytoin, phenobarbital
  • medicines to treat depression e.g. fluoxetine, fluvoxamine, paroxetine, mianserin, amitriptyline
  • medicines to treat mood disorder e.g. nefazodone, haloperidol, risperidone, lithium
  • medicines for sleep or anxiety e.g. alprazolam
  • medicines to treat asthma e.g. theophylline, aminophylline
  • medicines to treat fungal infections e.g. ketoconazole, itraconazole, fluconazole, miconazole
  • medicines to treat worm infections e.g. albendazole, mebendazole (only when used long-term)
  • antibiotics e.g. doxycycline, erythromycin, clarithromycin
  • medicines to treat TB (lung infection known as tuberculosis) e.g. isoniazid
  • medicines for HIV infection e.g. ritonavir
  • birth control pills
  • blood-thinning medicines e.g. warfarin
  • medicines for heart disease e.g. diltiazem, verapamil
  • medicines to treat high cholesterol e.g. simvastatin
  • medicines to treat cancer e.g. cisplatin, doxorubicin
  • other medicines such as danazol, ciclosporin, cimetidine
This list does not include all medicines that may interact with Carbamazepine.

As Carbamazepine may reduce the effectiveness of birth control pills, ask your doctor about the use of additional birth control methods.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicine, supplements and medicines that you buy without a prescription.

What special dietary instructions should I follow?

Avoid alcohol and grapefruit juice.

How should I store this medicine?

Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.

This information is independently developed by MIMS based on Carbamazepine - Oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2019 MIMS. All rights reserved. Powered by MIMS.com

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