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> Carbamazepine - Oral

Carbamazepine - Rectal - Patient Medicine Information

> Why do I need this medicine?
> How do I use this medicine?
> What should I do if I have forgotten to use this medicine?
> When should I not use this medicine?
> What should I take note of while using this medicine?
> What side effects could I experience?
> Can I take this with other medicines?
> What special dietary instructions should I follow?
> How should I store this medicine?

 

Why do I need this medicine?

Carbamazepine is used on its own or together with other medicines to treat epilepsy (also known as fits or seizures).

Carbamazepine suppository is for people who are temporarily unable to swallow oral medicine such as pills.

How do I use this medicine?

Use Carbamazepine exactly as directed by your doctor or according to the instructions on the label. Do not use more or less than instructed by your doctor.

Carbamazepine suppository is to be inserted into the rectum. Do not eat, chew or swallow it. Do not use it in any other way.

Try to go to the toilet before you insert the suppository.

Follow these steps:

1. Wash your hands thoroughly.

2. Remove the suppository from the foil wrapper.

3. If you are right-handed, lie on your left side and pull your right knee up to your chest.

4. Gently insert the suppository with the pointed end first into your rectum. Gently push the suppository as far as it would go.

5. Remain lying in this position for 10 -15 minutes to allow the suppository to melt. If you feel that the suppository is slipping out, press your buttocks together. The suppository must remain in the rectum so that the medicine can be absorbed.

Use it at the same time each day as directed by your doctor.

What should I do if I have forgotten to use this medicine?

Use the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

When should I not use this medicine?

Alert your doctor if you have the following conditions:

- history of bone marrow depression (a condition in which the blood cells are low)
- history of porphyria (an inherited disorder that may cause skin or nerve problems)
as Carbamazepine may not be suitable for you.

Do not take Carbamazepine if you are currently taking or have taken a medicine to treat depression known as a monoamine oxidase inhibitor (MAOI) such as isocarboxazid, phenelzine and tranylcypromine in the last 14 days.

What should I take note of while using this medicine?

Inform your doctor if you have:

- liver disease
- kidney disease
- heart disease
- blood disorders as a result of taking other medicines
- glaucoma (increased pressure in the eye)
- urinary problems
- long-term constipation
- mental illness or mood disorders
- an allergy to other epilepsy medicines such as phenytoin or oxcarbazepine or medicines to treat depression such as amitriptyline

Let your doctor know if you are pregnant or breastfeeding.

For as long as you are using Carbamazepine, you will need to have your eyes checked regularly. You may also need to have regular blood tests and urine tests. These tests help to monitor your body's response to Carbamazepine. Your doctor will advise you about how often you need to have these tests done.

If you are going for an operation, including minor operations and dental work, inform your doctor or dentist that you are using Carbamazepine.

What side effects could I experience?

Carbamazepine may cause drowsiness, tiredness and dizziness. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects include any of the following: irritation at the site of administration, headache, difficulty in controlling movements such as unsteadiness in walking or involuntary eye movements, double or blurred vision, nausea, vomiting, dry mouth, diarrhoea, constipation and itch. These side effects are common especially when you have just started taking Carbamazepine.

Some side effects may be serious, although they are not common. Alert your doctor quickly if you experience:

- rashes with peeling of the skin or blistering of the lips, mouth or eyes accompanied by fever
- swelling of the eyes, face or lips or breathing difficulties
- extensive or unusual bleeding or bruising
- mouth ulcers or persistent fever or sore throat
- yellowing of the skin or eyes with abdominal pain or persistent tiredness, nausea or vomiting
- confusion or hallucinations (seeing or hearing things that are not existent)
- unusual changes in mood or behaviour (being too depressed, agitated, or having thoughts of self-harm)

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.

Can I take this with other medicines?

Do not take Carbamazepine if you are currently taking or have taken a medicine to treat depression known as a MAOIs such as isocarboxazid, phenelzine and tranylcypromine in the last 14 days.

Inform your doctor and pharmacist if you are taking any of these medicines:

- other medicines for epilepsy e.g. valproic acid, clonazepam, phenytoin, phenobarbital
- medicines to treat depression e.g. fluoxetine, fluvoxamine, paroxetine, mianserin, amitriptyline
- medicines to treat mood disorders e.g. nefazodone, haloperidol, risperidone, lithium
- medicines for sleep or anxiety e.g. alprazolam
- medicines to treat asthma e.g. theophylline, aminophylline
- medicines to treat fungal infections e.g. ketoconazole, itraconazole, fluconazole, miconazole
- medicines to treat worm infections e.g. albendazole, mebendazole (only when used long-term)
- antibiotics e.g. doxycycline, erythromycin, clarithromycin
- medicines to treat TB (lung infection known as tuberculosis) e.g. isoniazid
- medicines for HIV infection e.g. ritonavir
- birth control pills
- blood-thinning medicines e.g. warfarin
- medicines for heart disease e.g. diltiazem, verapamil
- medicines to treat high cholesterol such as simvastatin
- medicines to treat cancer e.g. cisplatin, doxorubicin
- other medicines such as danazol, ciclosporin, cimetidine

This list does not include all medicines that may interact with Carbamazepine.

As Carbamazepine may reduce the effectiveness of birth control pills, ask your doctor about the use of additional birth control methods.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicine, supplements and medicines that you buy without a prescription.

What special dietary instructions should I follow?

Avoid alcohol and grapefruit juice.

How should I store this medicine?

Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.

This information is independently developed by MIMS based on Carbamazepine - Rectal and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2019 MIMS. All rights reserved. Powered by MIMS.com

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