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Dapagliflozin + Metformin - Oral - Patient Medicine Information

> Why do I need this medicine?
> How do I take this medicine?
> What should I do if I have forgotten to take this medicine?
> When should I not use this medicine?
> What should I take note of while taking this medicine?
> What side effects could I experience?
> Can I take this with other medicines?
> What special dietary instructions should I follow?
> How should I store this medicine?

 
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Why do I need this medicine?

Dapagliflozin and Metformin is combined together in this medicine.

Dapagliflozin + Metformin is used on its own or together with other medicines to treat type 2 diabetes (gradual loss of capacity of the pancreas to produce enough insulin). This medicine helps treat your diabetes by keeping your blood sugar in control.

Dapagliflozin + Metformin is meant to be taken as part of a complete diabetes care programme that should include exercise, a healthy diet and regular monitoring of blood sugar levels.

How do I take this medicine?

Take Dapagliflozin + Metformin exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

This medicine should be taken with food to decrease stomach upset. Try to take it at the same time each day.

If you are taking an extended-release type of tablet (usually labeled as “XR”), swallow it whole. Do not crush, cut or chew the tablet.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment regimen depending on the effectiveness and your tolerability to the medication.

Dapagliflozin + Metformin must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.

What should I do if I have forgotten to take this medicine?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.

When should I not use this medicine?

Alert your doctor if you have the following conditions:
  • moderate to severe kidney disease
  • acute or chronic metabolic acidosis (excessive acid production in the body e.g. lactic acidosis, ketoacidosis)
as Dapagliflozin + Metformin may not be suitable for you.

What should I take note of while taking this medicine?

Inform your doctor if you have the following conditions:
  • bladder cancer
  • liver disease
  • heart disease e.g. heart failure
  • stress related states e.g. fever, trauma, infection, surgery
This medicine is not intended for the treatment of type 1 diabetes (your body does not produce any insulin) or diabetes ketoacidosis (complication of diabetes characterised by high level of blood acid in your body).

Let your doctor know if you are pregnant or breastfeeding.

Be sure to check with your doctor or pharmacist before giving this medicine to an elderly. The elderly may be more sensitive to the side effects.

If you are going for an operation, including minor surgery and dental work, inform your doctor or dentist that you are taking Dapagliflozin + Metformin.

If you are going for diagnostic tests (e.g. urine tests, imaging procedures), inform your doctor that you are taking this medicine.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
  • You may need to have routine tests (e.g. blood sugar, vitamin B12 blood concentration, liver and kidney function). Your doctor will advise you about how often you need to have these tests.
  • Signs or symptoms of infections and other complications due to diabetes (e.g. metabolic acidosis) must be monitored.
You may have been warned about hypoglycaemia. Hypoglycaemia is the medical term for low blood sugar. It is important for you to recognise the symptoms of hypoglycaemia and correct the low blood sugar level. If you don't, you may faint.

How do I know if I am experiencing hypoglycaemia?

Some of the symptoms of hypoglycaemia include dizziness, headache, shaky hands, feeling hungry, weak or confused, problems speaking. These symptoms are your body's way of warning you that your blood sugar is dangerously low.

What should I do if I am experiencing hypoglycaemia?

You should take a drink or food containing sugar (e.g. fruit juice, soft drinks, sweets) at the first sign of hypoglycaemia. If your symptoms do not improve, get medical help. Keep some glucose tablets (also known as dextrose tablets) with you at all times.

What side effects could I experience?

Dapagliflozin + Metformin may cause dizziness. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects include any of the following: headache, nausea, vomiting, diarrhoea, stomach pain, loss of appetite, taste disturbance, back pain, and rash.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • signs of hypoglycaemia
  • signs of ketoacidosis or lactic acidosis e.g. nausea, vomiting, stomach pain, feeling sick, tiredness, difficulty breathing
  • signs of dehydration e.g. dry or sticky mouth, severe thirst, urinating less often or not at all
  • signs of infections of the urinary tract e.g. fever, chills, back pain, burning sensation when passing urine
  • signs of genital infection e.g. pain when passing urine, irritation or redness and swelling of genitals, unusual odour or discharge of your genitals
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.

Can I take this with other medicines?

Inform your doctor and pharmacist if you are taking any of these medicines:
  • other medicines for diabetes e.g. insulin, glimepiride, glipizide, glibenclamide
  • stomach medicines e.g. cimetidine
  • medicines for high blood pressure or heart disease e.g. ranolazine, nifedipine, propanolol, valsartan
  • medicines to treat cancer e.g. vandetanib
  • medicines for HIV infection e.g. dolutegravir
  • medicines for pain and inflammation (NSAIDs) e.g. mefenamic acid, ibuprofen
  • diuretics or “water pills” e.g. furosemide, hydrochlorothiazide
  • medicine for tuberculosis or TB e.g. rifampicin
This list does not include all medicines that may interact with Dapagliflozin + Metformin.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.

What special dietary instructions should I follow?

Avoid alcohol.

It is important for you to maintain a healthy diet and weight in order to help keep your diabetes under control.

How should I store this medicine?

Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.

This information is independently developed by MIMS based on Dapagliflozin + Metformin - Oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2019 MIMS. All rights reserved. Powered by MIMS.com

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