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Duloxetine - Oral - Patient Medicine Information

> Why do I need this medicine?
> How do I take this medicine?
> What should I do if I have forgotten to take this medicine?
> When should I not use this medicine?
> What should I take note of while taking this medicine?
> What side effects could I experience?
> Can I take this with other medicines?
> What special dietary instructions should I follow?
> How should I store this medicine?

 
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Why do I need this medicine?

Duloxetine is used to treat depression and anxiety.

It is also used to treat nerve pain in people who have diabetes or fibromyalgia (condition in which there is severe fatigue and muscle aches).

How do I take this medicine?

Take Duloxetine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

You may take Duloxetine with or without food. Try to take it at the same time each day.

Duloxetine must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed otherwise, as stopping it suddenly could worsen your condition.

What should I do if I have forgotten to take this medicine?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.

When should I not use this medicine?

Alert your doctor if you have:
  • severe kidney disease
  • liver disease
  • uncontrolled high blood pressure
as Duloxetine may not be suitable for you.

Do not take Duloxetine if you are currently taking a certain type of medicine to treat depression known as a monoamine oxidase inhibitor (MAOI) or within 14 days of stopping the MAOI. Do not take Duloxetine if you are taking linezolid (antibiotic).

What should I take note of while taking this medicine?

Inform your doctor if you have the following conditions:
  • mood disorders including bipolar disorder (mania and hypomania)
  • thoughts of suicide
  • glaucoma (increased pressure in the eye)
  • epilepsy (fits)
Let your doctor know if you are pregnant or breastfeeding.

Duloxetine is not meant for children and teenagers younger than 18 years old unless instructed by the doctor.

Medicines for depression such as Duloxetine may increase the risk of suicidal thoughts and behaviour. As depression and some psychiatric disorders are themselves associated with an increased risk of suicide, it is important for you or your family members to monitor your condition especially at the start of treatment and if your dosage is still being adjusted. If you experience new or sudden changes in mood, behaviour, thoughts or feelings or a worsening of your depression with suicidal thoughts or attempts, harm to self or harm to others, contact your doctor immediately.

What side effects could I experience?

Duloxetine may cause dizziness or drowsiness. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects include any of the following: nausea, headache, fatigue, insomnia, dry mouth, diarrhoea, constipation, dyspepsia, vomiting, difficulty sleeping, increased sweating, loss of appetite and stomach pain.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • unusual bruising or nosebleed
  • rashes with skin peeling or blisters / rashes with peeling of the skin or blistering of the lips, mouth or eyes accompanied by fever
  • yellowing of the eyes or skin
  • changes in sex drive
  • difficulty passing urine
  • hallucinations, delirium
  • very fast, irregular or pounding heartbeat
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.

Can I take this with other medicines?

Do not take Duloxetine if you are currently taking a certain type of medicine to treat depression known as a monoamine oxidase inhibitor (MAOI) such as selegiline, or within 14 days of stopping the MAOI. Do not take Duloxetine if you are taking linezolid (antibiotic).

Inform your doctor and pharmacist if you are taking any of these medicines:
  • other medicines for depression e.g. amitriptyline, desipramine, imipramine
  • medicines for heart disease e.g. flecainide, propafenone
  • medicines for migraine e.g. sumatriptan, zolmitriptan
  • painkillers e.g. tramadol, pethidine
  • St John's wort (herbal supplement)
  • warfarin (blood-thinning medicine)
This list does not include all medicines that may interact with Duloxetine.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.

What special dietary instructions should I follow?

Avoid alcohol.

How should I store this medicine?

Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.

This information is independently developed by MIMS based on Duloxetine - Oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2019 MIMS. All rights reserved. Powered by MIMS.com

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