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Filgrastim - Intravenous/Subcutaneous - Patient Medicine Information

> Why do I need this medicine?
> How do I use this medicine?
> What should I do if I have forgotten to use this medicine?
> When should I not use this medicine?
> What should I take note of while using this medicine?
> What side effects could I experience?
> Can I use this with other medicines?
> What special dietary instructions should I follow?
> How should I store this medicine?

 
Available Brands

Other Known Brands
  • Gran    

Why do I need this medicine?

Filgrastim is a growth factor known as granulocyte colony stimulating factor (G-CSF). Growth factor are substance which are produced naturally in the body but can also be made using technology for it to be used as a medicine.

It stimulates the growth of neutrophil, a type of white blood cell which helps your body to fight infections. It may be used in various conditions such as:
  • chemotherapy for cancer
  • receiving certain medical procedure e.g. bone marrow or stem cell transplant
  • severe neutropenia (abnormally low level of white blood cell)
  • receiving medicines for HIV infection

How do I use this medicine?

Filgrastim is to be injected subcutaneously (into the fatty layer under the skin) usually in the thigh or abdomen area. If you or your caregiver had been given the proper training on the preparation and injection techniques of this medicine, you or your caregiver may do the administration.

It may also be given intravenously (into the vein) and it is your doctor or nurse who will administer the injection for you.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the dosage and course of the treatment depending on your condition and response to the medication.

What should I do if I have forgotten to use this medicine?

Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Filgrastim.

If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.

If you or a caregiver had been trained to administer this medicine, inject the missed dose as soon as you remember and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to administer this medicine, let your doctor and pharmacist know.

When should I not use this medicine?

Alert your doctor if you have Kostmann’s syndrome (inherited blood disorder associated with severely low neutrophil level) as Filgrastim may not be suitable for you.

Do not use this medicine at the same time as chemotherapy.

Filgrastim should also not be used within 24 hours before or after receiving chemotherapy, radiation therapy, bone marrow or stem cell transplant.

What should I take note of while using this medicine?

Inform your doctor if you have the following conditions:
  • cancer of the bone marrow or blood
  • sickle-cell disease (condition in which there is no adequate red blood cells to carry oxygen throughout your body)
  • osteoporotic (thinning and weakening of the bone)
  • other medical conditions affecting bone marrow or blood
  • any infections, cancer or tumour
  • kidney problems
  • enlarged spleen (an organ located in the upper left part of the stomach that acts as a blood filter)
Let your doctor know if you are pregnant or breastfeeding.

Be sure to check with you doctor before giving this medicine to a child or an elderly.

If you are going to undergo certain medical procedures or tests (e.g. bone imaging), inform your doctor or dentist that you are being treated with this medicine.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly. Routine tests (e.g. complete blood count, bone marrow examination) may be done while you are being treated with this medicine. Your doctor will advise you about how often you will need to have these tests.

What side effects could I experience?

Filgrastim may cause any of the following side effects: headache, nausea, vomiting, diarrhoea, decreased appetite, dizziness, tiredness or weakness, fever, hair loss.

If you experience any bone or muscle pain while you are being treated with this medicine, it can be relieved by taking non-prescription painkillers (e.g. paracetamol). Inform your doctor if bone or muscle pain still persist after you have taken a pain reliever.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • pain in the upper left side of the stomach, left shoulder pain
  • shortness of breath or difficulty breathing
  • change in the amount of urine, urinate less than usual
  • rashes, breathlessness, swelling of the face, eyes, mouth or other parts of the body
  • unusual bleeding or bruising
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects

Can I use this with other medicines?

Inform your doctor and pharmacist if you are taking medicines for cancer e.g. belotecan, bleomycin, cyclophosphamide, tisagenlecleucel, topotecan.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.

What special dietary instructions should I follow?

Avoid alcohol.

How should I store this medicine?

Store in the refrigerator, between 2-8°C. Do not freeze otherwise it will no longer be effective and should not be used.

Store away from the reach of children. Protect from light.

Medicines must not be used past the expiry date.

This information is independently developed by MIMS based on Filgrastim - Intravenous/Subcutaneous and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2019 MIMS. All rights reserved. Powered by MIMS.com

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