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Imatinib - Oral - Patient Medicine Information

> Why do I need this medicine?
> How do I take this medicine?
> What should I do if I have forgotten to take this medicine?
> What should I take note of while taking this medicine?
> What side effects could I experience?
> Can I take this with other medicines?
> What special dietary instructions should I follow?
> How should I store this medicine?

 
Other Known Brands
  • Glivec    

Why do I need this medicine?

Imatinib is used to treat chronic myelogenous leukaemia or CML (a type of cancer where the bone marrow produces too many of the white blood cells called granulocytes).

This medicine is also used to treat cancer of the skin, stomach, and intestines.

How do I take this medicine?

Take Imatinib exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

This medicine should be taken together with a meal and a large glass of water.This will minimise the risk of irritation to the stomach. Try to take it at the same time each day.

If you have difficulty swallowing the tablet, you may either dissolve it in a glass of water or apple juice. Stir and drink it immediately. Do not divide, chew or crush the tablet.

Imatinib must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.

What should I do if I have forgotten to take this medicine?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, inform your doctor and pharmacist.

What should I take note of while taking this medicine?

Inform your doctor if you have the following conditions:

- liver disease
- kidney disease
- thyroid disease

It is important that you do not get pregnant while being treated with this medicine. You may wish to discuss birth control methods with your doctor or pharmacist.

Do not breastfeed while you are being treated with this medicine.

If you have undergone an operation such as surgery in your stomach, inform your doctor before taking Imatinib.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly. He may also need to do routine blood tests (e.g. complete blood count, liver function tests) while you are being treated with Imatinib. Your doctor will advise you about how often you need to have these tests.

What side effects could I experience?

Imatinib may cause any of the following side effects: diarrhoea, nausea, vomiting, indigestion, stomach pain, rashes, headaches, tiredness, and muscle and joint pain.

Some side effects may be serious, although they are not common. Alert your doctor quickly if you experience:

- rashes with skin peeling or blisters / rashes with peeling of the skin or blistering of the lips, mouth or eyes accompanied by fever
- pass out blood or black, tarry stools or vomit coffee-ground-like vomitus
- swelling in your legs and around your eyes
- fever with persistent sore throat or mouth ulcers, unusual bleeding or bruising

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.

Can I take this with other medicines?

Inform your doctor and pharmacist if you are taking any of these medicines:

- warfarin (a blood-thinning medicine)
- antibiotics e.g. erythromycin
- medicines to treat fungal infections e.g. ketoconazole, itraconazole
- medicines for epilepsy (fits or seizures) e.g. phenytoin, phenobarbital, carbamazepine
- medicines to treat TB (lung infection known as tuberculosis) e.g. rifampicin
- cholesterol-lowering medicines e.g. simvastatin, atorvastatin
- medicines for high blood pressure e.g. amlodipine, felodipine, nifedipine

This list does not include all medicines that may interact with Imatinib.

Always notify your doctor or pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.

What special dietary instructions should I follow?

Avoid alcohol and excessive consumption (more than 1 litre a day) of grapefruit juice.

How should I store this medicine?

Store in a cool, dry place away from the reach of children.

As this is a cancer medicine, always return any unused or expired tablets to the clinic, hospital or pharmacy for disposal. Do not throw it away in the household waste.

Medicines must not be used past the expiry date.

This information is independently developed by MIMS based on Imatinib - Oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2019 MIMS. All rights reserved. Powered by MIMS.com

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