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Itraconazole - Oral - Patient Medicine Information

> Why do I need this medicine?
> How do I take this medicine?
> What should I do if I have forgotten to take this medicine?
> When should I not use this medicine?
> What should I take note of while taking this medicine?
> What side effects could I experience?
> Can I take this with other medicines?
> What special dietary instructions should I follow?
> How should I store this medicine?

 
Available Brands

Other Known Brands
  • Inox    
  • Itracon    
  • Canditral    

Why do I need this medicine?

Itraconazole is used to treat fungal infections of the skin, nails, hands, feet, mouth, throat, digestive tract, vagina and other parts of the body.

This medicine may also be used to prevent fungal infections if you have weakened immune system due to viral or blood diseases.

Itraconazole may be used to treat other conditions as decided by your doctor.

How do I take this medicine?

Take Itraconazole exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Itraconazole is available as a tablet, capsule (conventional or pulse-release form), or as an oral solution.

If you have been given the tablet, conventional capsule or pulse-release capsule, take it immediately after a meal. Swallow it whole. Do not divide, chew, crush or break the tablet or capsule.

If you have been given the oral solution, take it on an empty stomach, at least 1 hour before meals. Use the measuring cup supplied with each bottle to measure out your dose. If you are taking this medicine due to mouth or throat infections, the oral solution should be swished vigorously in your mouth for a few seconds before swallowing.

Try to take Itraconazole at the same time each day.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on the type and severity of your infection.

This medicine must be taken regularly for it to be effective. Continue taking Itraconazole even when you feel better. Do not stop taking it unless instructed by the doctor.

Do not skip any doses. You must complete the entire course of medicine. If you don't, the infection will not be properly controlled.

What should I do if I have forgotten to take this medicine?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.

When should I not use this medicine?

Do not take Itraconazole if you ever had an allergic reaction (breathlessness, rashes, swollen eyes) to this medicine.

Alert your doctor if you have or had a history of heart disease (e.g. heart failure) as this medicine may not be suitable for you.

Do not take Itraconazole if you are pregnant or planning to have a baby soon. If you become pregnant while being treated with this medicine, alert your doctor immediately. Itraconazole may cause harm to your unborn child. You must use proven birth control methods while taking this medicine.

Do not take Itraconazole with medicines for irregular heartbeat, chest pain, high blood pressure, cold or allergy, migraine, mood disorder, digestive problems, cancer, malaria, lowering cholesterol levels, and gout. Please see the section “Can I take this with other medicines?” below for more information.

What should I take note of while taking this medicine?

Inform your doctor if you have the following conditions:
  • kidney disease
  • liver disease
  • heart disease e.g. heart valve disorders
  • cystic fibrosis (inherited disease that causes excessively thick and sticky mucus build up in the lungs or intestines)
  • achlorhydria (absence or low production of acid in the stomach)
  • weakened immune system due to certain conditions (e.g. blood diseases, AIDS, organ transplantation)
Let your doctor know if you are pregnant or breastfeeding.

Be sure to check with your doctor or pharmacist before giving this medicine to an elderly.

Maintain good hygiene as this is important in managing fungal infections.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly. Routine blood tests to check your kidney and liver function may be needed while you are being treated with Itraconazole. Your doctor will advise you about how often you will need to have these tests.

What side effects could I experience?

Itraconazole may cause dizziness or some problems with your eyesight or sense of hearing. If affected, do not drive or take part in any activity in which you need to be alert.

This medicine may cause any of the following side effects: headache, ringing in the ears, cough, nausea, vomiting, indigestion, constipation, diarrhoea, and skin rash.

If you develop rashes, breathlessness, swollen mouth or eyes, stop taking Itraconazole and inform your doctor quickly. These could be signs of an allergic reaction.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • numbness or tingling sensation in the hands and feet
  • hearing problems or loss
  • shortness of breath, swelling of the feet, legs or stomach, unexpected sudden weight gain
  • severe persistent stomach pain, unusual tiredness, dark urine, pale stool, yellowing of the skin or eyes
  • rashes with peeling or blistering of the skin, lips, mouth, eyes or genitals accompanied by fever
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.

Can I take this with other medicines?

Do not take Itraconazole if you are taking any of these medicines:
  • medicines for irregular heartbeat e.g. quinidine, dronedarone, dofetilide, disopyramide
  • medicines for chest pain and high blood pressure e.g. bepridil, felodipine, lercanidipine, nisoldipine, ranolazine
  • medicines for cold or allergy e.g. terfenadine, astemizole, mizolastine
  • medicines for migraine e.g. dihydroergotamine, ergotamine
  • medicines for mood disorders e.g. pimozide, sertindole, lurasidone
  • medicines for anxiety e.g. oral midazolam, triazolam
  • cisapride (medicine for digestive problems)
  • irinotecan (medicine for cancer)
  • halofantrine (medicine used to treat malaria)
  • cholesterol-lowering medicines e.g. simvastatin, lovastatin
  • eplerenone (medicine for water retention or “water pills”)
  • colchicine (medicine for gout) when used to those with kidney or liver problems
Inform your doctor and pharmacist if you are also taking any of these medicines:
  • medicines used in organ transplant or certain immune disorders e.g. ciclosporin, tacrolimus
  • medicines used to treat tuberculosis or TB e.g. rifampicin, rifabutin, isoniazid
  • medicines to treat epilepsy (seizures or fits) e.g. carbamazepine, phenytoin, phenobarbital
  • medicines for HIV infection e.g. indinavir, ritonavir, saquinavir, nevirapine, efavirenz
  • medicines for high blood pressure or heart disease e.g. verapamil, digoxin, nadolol
  • blood-thinning medicines e.g. warfarin, cilostazol, apixaban
  • medicines for cancer e.g. vinca alkaloids, busulfan, docetaxel
  • medicines for anxiety e.g. alprazolam, buspirone
  • certain antibiotics e.g. erythromycin, clarithromycin, ciprofloxacin
  • medicines for inflammation, asthma or allergies e.g. budesonide, dexamethasone, methylprednisolone
  • medicines to neutralise stomach acids e.g. antacids, ranitidine, omeprazole
  • strong painkillers e.g. fentanyl, alfentanil, oxycodone
This list does not include all medicines that may interact with Itraconazole.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.

What special dietary instructions should I follow?

Avoid alcohol.

How should I store this medicine?

Store in a cool, dry place away from the reach of children.

Keep tablets or capsules in their original package to protect from light and moisture.

The oral solution can be stored at room temperature not more than 25°C. Do not freeze. It should be used within 1 month after opening.

Medicines must not be used past the expiry date.

This information is independently developed by MIMS based on Itraconazole - Oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2019 MIMS. All rights reserved. Powered by MIMS.com

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