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Mirtazapine - Oral - Patient Medicine Information

> Why do I need this medicine?
> How do I take this medicine?
> What should I do if I have forgotten to take this medicine?
> When should I not use this medicine?
> What should I take note of while taking this medicine?
> What side effects could I experience?
> Can I take this with other medicines?
> What special dietary instructions should I follow?
> How should I store this medicine?

 
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Why do I need this medicine?

Mirtazapine is used to treat depression.

How do I take this medicine?

Take Mirtazapine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

This medicine should be taken with or without food. Try to take it at the same time each day.

Mirtazapine is available as a tablet or orodispersible tablet (orally disintegrating tablet).

If you are taking the conventional tablet, swallow it whole. Do not chew or crush it.

If you are taking the orally disintegrating tablet:

1. Remove it from the foil only just before you take it. Do not leave the orodispersible tablet exposed to air. Do not push the orodispersible tablet through the foil as it is fragile and easily broken.
2. Remove the orodispersible tablet with dry hands by peeling the backing off the foil and tipping the tablet onto your dry hands.
3. Place the orodispersible tablet directly on your tongue as soon as it taken out of the foil. The orodispersible tablet will start to melt on the tongue very quickly. Swallow it with or without water.

Do not cut, break or crush the orodispersible tablets.

Mirtazapine must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed otherwise, as stopping it suddenly could worsen your condition.

What should I do if I have forgotten to take this medicine?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.

When should I not use this medicine?

Do not take Mirtazapine if you are taking or have taken other mood medicines known as monoamine oxidase inhibitors (MAOIs) such as isocarboxacid, phenelzine and tranylcypromine in the last 14 days.

What should I take note of while taking this medicine?

Inform the doctor if you have the following:

- liver disease
- kidney disease
- heart disease
- low blood pressure
- history of epilepsy (fits) or head injury
- diabetes
- prostate enlargement or problems passing urine
- bipolar disorder or mood changes between feeling very high (mania) and very low (depression)

Let your doctor know if you are pregnant or breastfeeding.

What lifestyle changes should I make to cope with depression?

Regular exercise and eating a healthy diet will help increase energy and hormones in the body such as happy hormones that minimise mood swings. Get enough sleep, as lack of sleep may cause irritability, moodiness, sadness, and tiredness.

What side effects could I experience?

Mirtazapine may cause drowsiness, dizziness and tiredness. It may also cause you to suddenly fall asleep during your daily activities such as eating and watching television. You may not feel drowsy before you fall asleep. If affected, do not drive or take part in any activity in which you need to be alert.

This medicine may cause your blood pressure to fall suddenly when you get up from a sitting or lying down position and you may feel giddy. To minimise this problem, stand up slowly.

Other side effect may include any of the following: headache, dry mouth, constipation, nausea, vomiting, increased appetite, weight gain, weakness, difficulty in sleeping, confusion and anxiety.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:

- confusion and hallucinations (seeing, hearing or feeling things that are not existent)
- unpleasant or distressing restlessness and need to move often with an inability to sit or stand still
- unusual bleeding or bruising and frequent and persistent sore throat with fever
- unusual changes in mood or behaviour (being too depressed, agitated, or having thoughts of self harm)
- yellowing of the skin, eyes, pain near the stomach area

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.

Can I take this with other medicines?

Do not take Mirtazapine if you are taking or have taken other mood medicines known as monoamine oxidase inhibitors (MAOIs) such as isocarboxacid, phenelzine and tranylcypromine in the last 14 days.

Inform your doctor and pharmacist if you are taking any of these medicines:

- medicines for mood disorders e.g. nefazodone, venlafaxine, fluoxetine
- antibiotic e.g. erythromycin, linezolid
- cimetidine (medicines for gastric disorders)
- warfarin (blood-thinning medicines)
- medicines to treat fungal infections e.g. ketoconazole, fluconazole
- medicines to treat HIV e.g. indinavir, ritonavir
- medicine for moderate to severe pain e.g. tramadol

This list does not include all medicines that may interact with Mirtazapine

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.

What special dietary instructions should I follow?

Avoid alcohol.

How should I store this medicine?

Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.

This information is independently developed by MIMS based on Mirtazapine - Oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2019 MIMS. All rights reserved. Powered by MIMS.com

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