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Olanzapine+Fluoxetine - Oral - Patient Medicine Information

> Why do I need this medicine?
> How do I take this medicine?
> What should I do if I have forgotten to take this medicine?
> When should I not use this medicine?
> What should I take note of while taking this medicine?
> What side effects could I experience?
> Can I take this with other medicines?
> What special dietary instructions should I follow?
> How should I store this medicine?

 

Why do I need this medicine?

Olanzapine and Fluoxetine are combined together in this medicine.

Olanzapine+Fluoxetine is used to treat a dysfunctional mood condition known as bipolar disorder that occurs with depression.

How do I take this medicine?

Take Olanzapine+Fluoxetine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

You may take this medicine with or without food. Try to take it at the same time every day.

Olanzapine+Fluoxetine must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed otherwise, as stopping it suddenly could worsen your condition.

What should I do if I have forgotten to take this medicine?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.

When should I not use this medicine?

Do not take a certain type of medicine to treat depression known as a monoamine oxidase inhibitor (MAOI) within 5 weeks of stopping Olanzapine+Fluoxetine, or take Olanzapine+Fluoxetine within 2 weeks of stopping the MAOI. Do not take Olanzapine+Fluoxetine if you are taking linezolid (antibiotic) or pimozide (medicine for uncontrolled movements).

Do not take thioridazine (medicine for mood disorder) within 5 weeks of stopping Olanzapine+Fluoxetine.

What should I take note of while taking this medicine?

Inform your doctor if you have the following conditions:

- dementia (decline in mental ability)
- mood disorders including bipolar disorder (mania and hypomania)
- Parkinson's disease (a brain disease that affects movement)
- diabetes
- epilepsy (fits)
- liver or kidney disease
- heart disease
- have a history of bleeding disorders
- glaucoma (increased pressure in the eye)
- having thoughts of self-harm

Let your doctor know if you are pregnant or breastfeeding.

Alert your doctor if you have recently undergone electroshock therapy (also known as electroconvulsive therapy or ECT).

Olanzapine+Fluoxetine is not meant for children and teenagers younger than 18 years old unless instructed by the doctor.

Medicines for depression such as Olanzapine+Fluoxetine may increase the risk of suicidal thoughts and behaviour. As depression and some psychiatric disorders are themselves associated with an increased risk of suicide, it is important for you or your family members to monitor your condition especially at the start of treatment and if your dosage is still being adjusted. If you experience new or sudden changes in mood, behaviour, thoughts or feelings or a worsening of your depression with suicidal thoughts or attempts, harm to self or harm to others, contact your doctor immediately.

What side effects could I experience?

Olanzapine+Fluoxetine may cause drowsiness and blurred vision. If affected, do not drive or take part in any activity in which you need to be alert or be able to see clearly.

This medicine may cause you to suddenly fall asleep during your daily activities such as eating and watching television. You may not feel drowsy before you fall asleep.

Other side effects may include any of the following: increased appetite, weight gain, dry mouth, difficulty concentrating, tiredness and tremors.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:

- unusual bruising or nosebleed
- unexplained bone pain, swelling
- very fast, irregular or pounding heartbeat
- difficulty in breathing
- hallucinations, delirium
- rashes with skin peeling or blisters / rashes with peeling of the skin or blistering of the lips, mouth or eyes accompanied by fever
- changes in sex drive

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.

Can I take this with other medicines?

Do not take a certain type of medicine to treat depression known as a monoamine oxidase inhibitor (MAOI) within 5 weeks of stopping Olanzapine+Fluoxetine, or take Olanzapine+Fluoxetine within 2 weeks of stopping the MAOI. Do not take Olanzapine+Fluoxetine if you are taking linezolid (antibiotic) or pimozide (medicine for uncontrolled movements).

Do not take thioridazine (medicine for mood disorder) within 5 weeks of stopping Olanzapine+Fluoxetine.

Inform your doctor and pharmacist if you are taking any of these medicines:

- mood medicines e.g. clomipramine, chlorpromazine, haloperidol, lithium
- sleeping pills or anxiety medication e.g. diazepam, alprazolam
- blood-thinning medicines e.g. warfarin, clopidogrel, dipyridamole
- medicines for pain and inflammation (NSAIDs) e.g. ibuprofen
- medicines for the heart e.g. flecainide, propafenone
- medicines for epilepsy (fits) e.g. phenytoin, carbamazepine
- medicines for Parkinson's disease e.g. levodopa
- St John's wort (herbal supplement)

This list does not include all medicines that may interact with Olanzapine+Fluoxetine.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.

What special dietary instructions should I follow?

Avoid alcohol.

How should I store this medicine?

Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.

This information is independently developed by MIMS based on Olanzapine+Fluoxetine - Oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2019 MIMS. All rights reserved. Powered by MIMS.com

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