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Perindopril + Indapamide - Oral - Patient Medicine Information

> Why do I need this medicine?
> How do I take this medicine?
> What should I do if I have forgotten to take this medicine?
> When should I not use this medicine?
> What should I take note of while taking this medicine?
> What side effects could I experience?
> Can I take this with other medicines?
> What special dietary instructions should I follow?
> How should I store this medicine?

 
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Why do I need this medicine?

Perindopril and Indapamide are combined together in this medicine. This medicine helps keep your blood pressure under control.

Perindopril helps your blood pressure to go down by relaxing the blood vessels. Indapamide removes excess water and salts from the body by passing them into the urine. This reduces the amount of water in the body and thus reduces the blood pressure.

How do I take this medicine?

Take Perindopril + Indapamide exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take this medicine on an empty stomach, at least 1 hour before or 2 hours after a meal. Try to take it at the same time each day.

Perindopril + Indapamide must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.

What should I do if I have forgotten to take this medicine?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.

When should I not use this medicine?

Do not take Perindopril + Indapamide if you ever had an allergic reaction (swollen extremities, face and throat; difficulty swallowing or breathing, rashes) due to similar medicines (e.g. captopril), an unknown reason or family history.

Alert your doctor if you have the following conditions:
  • severe kidney disease
  • severe liver disease
  • low potassium levels in the blood
  • unable to pass urine
as this medicine may not be suitable for you.

Do not take Perindopril + Indapamide if you are pregnant or planning to have a baby soon. If you become pregnant while being treated with this medicine, alert your doctor immediately. Perindopril + Indapamide may cause harm to your unborn child. Discuss the use of appropriate birth control methods with your doctor while being treated with this medicine.

Do not take Perindopril + Indapamide if you are breastfeeding.

Do not take this medicine with aliskiren (medicine to help keep blood pressure under control) if you have diabetes.

Do not take Perindopril + Indapamide with medicines for irregular heartbeat (e.g. amiodarone, sotalol, procainamide, quinidine).

What should I take note of while taking this medicine?

Inform your doctor if you have the following conditions:
  • electrolyte imbalance (imbalance of minerals in the body)
  • immune system diseases affecting collagen
  • diabetes
  • gout
  • heart disease e.g. narrowing of the valves of the heart
  • liver disease
Let your doctor know if you are breastfeeding.

If you are to undergo dialysis, apheresis (a procedure which involves separation of components of the blood), surgery or certain laboratory tests, inform your doctor that you are taking this medicine.

For as long as you are taking Quinapril + Hydrochlorothiazide, you may need to have regular monitoring of your blood pressure to check your body’s response to the medicine. You may also need to have regular blood tests for your body’s electrolyte levels and kidney function. Your doctor will advise you how often you need to have them.

What lifestyle changes can I make to improve my blood pressure?

Regular exercise and eating a healthy diet will help lower your blood pressure and improve your overall health. Engage in physical activity (e.g. walking) at least 30 to 60 minutes on most days of the week. If you have not exercised for a long time, start with light exercises such as slow walks. Speak to your doctor about what type of exercise would be suitable for you. Follow a healthy diet plan by eating more fruits, vegetables, whole grains and low-fat dairy products and reduce your intake of foods high in saturated fat, cholesterol and sodium. Cutting down on deep-fried foods and using less salt when cooking can kick-start your healthy diet.

If you smoke, you should try to quit. Smoking is harmful to your blood pressure, heart and overall health. Speak to your doctor or pharmacist about ways to kick your smoking habit.

Try to keep stress levels under control as stress will cause your blood pressure to go up.

What side effects could I experience?

Perindopril + Indapamide may cause dizziness and blurred vision. If affected, do not drive or take part in any activity in which you need to be alert or to see clearly.

You may also feel dizzy when getting up from a sitting or lying down position, especially if you are taking Perindopril + Indapamide for the very first time. This is common and should improve gradually as you get used to this medicine. It will help if you get up slowly from a sitting or lying down position. If you are taking Perindopril + Indapamide for the very first time, take the first dose of this medicine at bedtime to minimise dizziness.

Other side effects may include any of the following: headache, weakness, tiredness, muscle cramps, numbness or tingling sensation in the hands and feet, cough, nausea, vomiting, diarrhoea, constipation, stomach discomfort or pain, ringing in the ears, loss of taste perception, rash, itching and sensitivity of the skin to sunlight. Apply sunscreen when going outdoors and avoid direct or prolonged exposure to sunlight and UV lamps.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • swollen extremities, face and throat; difficulty swallowing or breathing, rashes
  • yellowing of the skin or eyes, stomach pain
  • eye pain, blurring of vision
  • fever with persistent sore throat or mouth ulcers, unusual bleeding or bruising
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.

Can I take this with other medicines?

Do not take Perindopril + Indapamide with aliskiren (medicine to help keep blood pressure under control) if you have diabetes.

Do not take this medicine with medicines for irregular heartbeat (e.g. amiodarone, sotalol, quinidine).

Inform your doctor or pharmacist if you are taking any of these medicines:
  • other diuretics (water pills) e.g. amiloride, eplerenone, spironolactone, triamterene
  • baclofen (muscle relaxant)
  • medicine for heart disease e.g. digoxin
  • medicine for pain and inflammation e.g. aspirin
  • medicines for mood disorders e.g. lithium
  • medicines to treat depression e.g. imipramine
  • medicines for diabetes e.g. insulin, metformin, linagliptin
  • medicines for gout e.g. allopurinol
  • medicines used in certain immune disorders e.g. corticosteroids
This list does not include all medicines that may interact with Perindopril + Indapamide.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicine, supplements and medicines that you buy without a prescription.

What special dietary instructions should I follow?

Avoid alcohol.

Cut down on your salt intake. This may help lower your blood pressure and improve your overall health. Speak to your doctor or dietitian about ways to cut down on your salt intake.

Do not take potassium supplements. Avoid taking too much food that is high in potassium, such as orange juice, bananas or prunes. Do not use salt substitutes that contain potassium.

How should I store this medicine?

Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.

This information is independently developed by MIMS based on Perindopril + Indapamide - Oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2019 MIMS. All rights reserved. Powered by MIMS.com

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