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Saxagliptin + Metformin - Oral - Patient Medicine Information

> Why do I need this medicine?
> How do I take this medicine?
> What should I do if I have forgotten to take this medicine?
> When should I not use this medicine?
> What should I take note of while taking this medicine?
> What side effects could I experience?
> Can I take this with other medicines?
> What special dietary instructions should I follow?
> How should I store this medicine?

 
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Why do I need this medicine?

Saxagliptin and Metformin are combined together in this medicine.

Saxagliptin + Metformin is used on its own or together with other medicines to treat type 2 diabetes (gradual loss of capacity of the pancreas to produce enough insulin). This medicine helps treat your diabetes by keeping your blood sugar in control.

Saxagliptin + Metformin is meant to be taken as part of a complete diabetes care programme that should include exercise, a healthy diet and regular monitoring of blood sugar.

How do I take this medicine?

Take Saxagliptin + Metformin exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take it together with food or immediately after a meal. Try to take it at the same time each day.

If you are taking the sustained-release, prolonged-release or extended-release type of tablet (usually labeled as “SR”, “XL” or “ER”), swallow it whole. Do not divide, chew or crush the tablet.

This medicine must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed otherwise, as stopping it suddenly could worsen your condition.

What should I do if I have forgotten to take this medicine?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.

When should I not use this medicine?

Alert your doctor if you have the following conditions:
  • conditions that may affect kidney function (e.g. excessive water loss from the body and severe infections)
  • conditions that may cause inadequate oxygen supply (e.g. recent heart attack)
  • moderate to severe kidney disease
  • liver disease
  • acute or chronic metabolic acidosis (excessive acid production in the body e.g. lactic acidosis, ketoacidosis)
as Saxagliptin + Metformin may not be suitable for you.

Do not breastfeed while being treated with this medicine.

What should I take note of while taking this medicine?

Inform your doctor if you have the following conditions:
  • heart failure
  • current or history of pancreas inflammation
  • stress related states e.g. fever, trauma, infection, surgery
You are more likely to develop lactic acidosis (too much lactic acid accumulation in the body) while you are being treated with Saxagliptin + Metformin. You may be having lactic acidosis if you experience vomiting,  stomach pain, extreme tiredness, unusual muscle pain, drowsiness or dizziness.

Let your doctor know if you are pregnant.

If you are going for an operation, including minor surgery and dental work, or imaging procedure that uses iodinated contrast agents, inform your doctor or dentist that you are taking this medicine.

Notify your doctor if you consume large amounts of alcohol or if you are a frequent drinker.

You may see a small tablet-shaped casing in your bowel movements. This is normal; do not be alarmed. This casing is just an empty shell; the medicine inside it has already been absorbed by your body.

If you are taking this medicine with other types of oral anti-diabetic medicines, you may have been warned about hypoglycaemia (low blood sugar). This medicine itself does not usually cause hypoglycaemia, but it may increase the hypoglycaemic effect of other oral anti-diabetic medicines.

How do I know if I am experiencing hypoglycaemia?

Hypoglycaemia is the medical term for low blood sugar. Symptoms of hypoglycaemia include dizziness, tremor, shaky hands, feeling hungry, weak or confused, problems speaking – these signs are your body’s way of warning you that your blood sugar level is dangerously low.

It is important to recognise these symptoms and get relief for hypoglycaemia quickly, as the hypoglycaemia could worsen and you might faint.

What should I do if I am experiencing hypoglycaemia?

Always carry some glucose tablets (also known as dextrose tablets) with you. Take a tablet at the first sign of hypoglycaemia. As Acarbose prevents the digestion of other kinds of sugar, only glucose (dextrose) tablets should be used to treat hypoglycaemia if you are on this medicine.

What side effects could I experience?

Saxagliptin + Metformin may cause any of the following side effects: increased risk of infections, headache and rash.

Other side effects include any of the following: nausea, vomiting, abdominal pain, metallic taste in the mouth and loss of appetite.

Some side effects may be serious, although they are not common. Alert your doctor quickly if you experience:
  • muscle pain, tiredness, breathing distress, drowsiness and abdominal discomfort without any identifiable causes
  • persistent and severe abdominal pain
  • severe joint pain
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.

Can I take this with other medicines?

Inform your doctor and pharmacist if you are taking any of these medicines:
  • medicine to treat tuberculosis e.g. rifampicin
  • medicines to treat fungal infection e.g. ketoconazole
  • medicines to relieve stomach discomfort e.g. cimetidine
  • medicines for high blood pressure or heart disease e.g. diuretics, diltiazem, enalapril
  • medicine for diabetes e.g. insulin
  • anti-inflammatory medicine e.g. NSAIDs (medicine for pain and inflammation), glucocorticoids
This list does not include all medicines that may interact with Saxagliptin + Metformin.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.

What special dietary instructions should I follow?

Avoid alcohol.

It is important for you to maintain a healthy diet and weight in order to help keep your diabetes under control.

How should I store this medicine?

Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.

This information is independently developed by MIMS based on Saxagliptin + Metformin - Oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2019 MIMS. All rights reserved. Powered by MIMS.com

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