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Tibolone - Oral - Patient Medicine Information

> Why do I need this medicine?
> How do I take this medicine?
> What should I do if I have forgotten to take this medicine?
> When should I not use this medicine?
> What should I take note of while taking this medicine?
> What side effects could I experience?
> Can I take this with other medicines?
> What special dietary instructions should I follow?
> How should I store this medicine?

 
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Why do I need this medicine?

Tibolone is a hormone replacement therapy used to treat oestrogen deficiency symptoms (e.g. hot flushes) in postmenopausal women (at least 12 months since the last natural period).

This medicine may also be used to prevent postmenopausal osteoporosis (thinning and weakening of bones).

How do I take this medicine?

Take Tibolone exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Swallow the tablet with some water or other non-alcoholic drink. Take it at the same time each day.

This medicine comes in a strip of tablets that are marked with the days of the week. Take the tablet accordingly. For example, if it is a Monday, take the tablet marked as Monday on the top row of the strip. Follow the arrows (days of the week) until the strip is empty. Do not leave a break between strips.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the course of your treatment depending on your condition and response to the medication.

What should I do if I have forgotten to take this medicine?

Take the missed dose as soon as you remember. If it is more than 12 hours overdue from your scheduled dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.

When should I not use this medicine?

Alert your doctor if you have the following conditions:
  • cancer of the breast, womb or ovaries
  • unexplained vaginal bleeding
  • excessive thickening of the womb
  • blood clotting in a vein such as in the legs or lungs
  • blood disorders
  • recent stroke or heart attack
  • liver disease
  • porphyria (an inherited disorder that causes skin or nerve abnormalities)
as Tibolone may not be suitable for you.

Do not take this medicine if you are pregnant or breastfeeding.

What should I take note of while taking this medicine?

Inform your doctor if you have the following conditions:
  • abnormal growth of tissues of the womb or the tissues outside the womb
  • increased risk of developing blood clot disorders (e.g. major surgery, obesity, long term immobility)
  • increased risk of developing an oestrogen sensitive cancer (e.g. family history of breast cancer)
  • high blood pressure
  • diabetes
  • gallstone
  • migraine
  • systemic lupus erythematosus (autoimmune disease that causes inflammation)
  • epilepsy (fits or seizures)
  • asthma
  • otosclerosis (hearing disorder due to abnormal growth of bone in the ear)
If you are going to have an operation, including minor surgery, inform your doctor that you are taking Tibolone.

To check the appropriateness of initiating Tibolone treatment, your doctor will ask you of your medical history. Physical examination may also be needed to assess if this medicine is suited for you.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly. Routine tests (e.g. breast examination, cervical smear test) may be done while you are being treated with this medicine. Your doctor will advise you about how often you will need to have these tests.

What side effects could I experience?

Tibolone may cause any of the following side effects: breast, vaginal or pelvic pain, unusual hair growth, and vaginal discharge, itching, irritation, bleeding or spotting.

Other side effects may include any of the following: headache, dizziness, stomach upset or discomfort, joint or muscle pain, acne, and skin rash or itching.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • severe, persistent vaginal bleeding
  • pain, swelling and tenderness in your leg
  • yellowing of the skin or eyes
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.

Can I take this with other medicines?

Inform your doctor and pharmacist if you are taking any of these medicines:
  • warfarin (blood-thinning medicine)
  • medicines for epilepsy (fits or seizures) e.g. carbamazepine, phenytoin
  • rifampicin (medicine for tuberculosis)
  • St. John's wort (herbal medicine)
This list does not include all medicines that may interact with Tibolone.

Always notify your doctor if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.

What special dietary instructions should I follow?

Avoid alcohol.

How should I store this medicine?

Store in a cool, dry place away from the reach of children.

Keep tablets in their original package to protect from light and moisture.

Medicines must not be used past the expiry date.

This information is independently developed by MIMS based on Tibolone - Oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2019 MIMS. All rights reserved. Powered by MIMS.com

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