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Tioguanine - Oral - Patient Medicine Information

> Why do I need this medicine?
> How do I take this medicine?
> What should I do if I have forgotten to take this medicine?
> When should I not use this medicine?
> What should I take note of while taking this medicine?
> What side effects could I experience?
> Can I take this with other medicines?
> What special dietary instructions should I follow?
> How should I store this medicine?

 
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Why do I need this medicine?

Tioguanine is used on its own or together with other medicines to treat cancer of the white blood cells (leukaemia).

How do I take this medicine?

Take Tioguanine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take this medicine on an empty stomach. Try to take it at the same time each day.

What should I do if I have forgotten to take this medicine?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.

When should I not use this medicine?

Alert your doctor if you had been resistant to prior therapy with Tioguanine.

Do not take this medicine if you are pregnant or planning to have a baby soon. If you become pregnant while being treated with Tioguanine, alert your doctor immediately. This medicine may cause harm to your unborn child. You must use proven birth control methods while taking this medicine.

Do not breastfeed while you are being treated with this medicine.

What should I take note of while taking this medicine?

Inform your doctor if you have the following conditions:

- liver disease
- kidney disease
- your body lacks an enzyme called thiopurine methyltransferase (TPMT)

Inform your doctor if you are planning to have a vaccination or if you recently had one.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly. Routine blood tests and liver function tests may be needed while you are being treated with this medicine. Your doctor will advise you about how often you need to have these tests.

What side effects could I experience?

Tioguanine may cause any of the following side effects: nausea, vomiting, mouth sores and loss of appetite.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:

- signs of infection (fever, chills, sore throat or mouth ulcer)
- unusual bleeding or bruising
- yellowing of the skin or eyes

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.

Can I take this with other medicines?

Inform your doctor and pharmacist if you are taking any of these medicines:

- medicines to treat cancer e.g. busulfan
- medicines to treat inflammation of the intestines e.g. sulfasalazine, mesalazine, olsalazine

This list does not include all medicines that may interact with Tioguanine.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.

What special dietary instructions should I follow?

Avoid alcohol.

How should I store this medicine?

Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.

As Tioguanine is a cancer medicine, always return any unused or expired tablet to the clinic, hospital or pharmacy for disposal. Do not throw it away in the household waste.

This information is independently developed by MIMS based on Tioguanine - Oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2019 MIMS. All rights reserved. Powered by MIMS.com

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