Ardeparin


Concise Prescribing Info
Indications/Uses
Prophylaxis of post-op venous thromboembolism.
Dosage/Direction for Use
Adult : SC Initial: 50 IU/kg after surgery, then 50 IU/kg twice daily for 14 days or until ambulatory.
Dosage Details
Subcutaneous
Prophylaxis of deep vein thrombosis
Adult: Initially 50 iu/kg following surgery. Subsequently, 50 iu/kg bid for 14 days after surgery or until ambulatory.
Contraindications
Hypersensitivity, thrombocytopaenia, active major bleeding, active peptic ulcer.
Special Precautions
Renal or hepatic impairment, history of GI ulceration, uncontrolled hypertension, spinal or epidural anaesthesia. Pregnancy, lactation; elderly. Periodic blood counts, including platelet count and stool occult blood test recommended.
Adverse Reactions
Thrombocytopaenia, mild bleeding, Inj site irritation, pain and ecchymoses, hypersensitivity and erythema.
Potentially Fatal: Haemorrhagic complications.
Drug Interactions
Potentially Fatal: Risk of haemorrhage increased with oral anticoagulants, platelet aggregation inhibitors, NSAIDs including aspirin.
Action
Description: Ardeparin Na is a LMWH with anticoagulant activity. It has been used for the prevention of post-op venous thromboembolism.
Pharmacokinetics:
Excretion: Elimination half-life: 3.5 hr.
Disclaimer: This information is independently developed by MIMS based on Ardeparin from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in