Avarin

Avarin

Manufacturer:

Mega Lifesciences

Distributor:

Maxxcare
Full Prescribing Info
Contents
Simethicone, Alverine Citrate.
Description
Each softgel capsule contains: Simethicone 300 mg, Alverine Citrate 60 mg.
Excipients/Inactive Ingredients: Silicon dioxide, gelatin, glycerin, purified water, iron oxide yellow, brilliant blue, iron oxide black, titanium dioxide.
Action
Pharmacology: Alverine citrate is a smooth muscle antispasmodic which is approximately 3 times as potent as papaverine and with a longer duration of action. It is neither an anticholinergic nor a derivative of atropine. Its direct spasmolytic action appears to be due to the local anesthetic properties of the drug. It has not been found to block ganglionic or skeletal neuromuscular transmission, nor to significantly reduce gastric or pancreatic secretion.
The clinical use of simethicone is based on its antifoam properties. Silicone antifoams spread on the surface of aqueous liquids, forming a film of low surface tension and thus causing collapse of foam bubbles. Simethicone reportedly allows mucus-surrounded gas bubbles in the GI tract to coalesce and be expelled.
Indications/Uses
Symptomatic treatment of gastrointestinal disorders such as irritable bowel syndrome or peptic ulcer and that consists of abdominal discomfort (bloating, distention, fullness, pain and/or cramps).
It is also used in the treatment of dysmenorrhea.
Dosage/Direction for Use
Adults: One capsule 1-3 times daily after meals or as directed by physician.
Overdosage
In case of overdosage, please consult the physician.
Contraindications
Hypersensitivity to any components of product.
Patients with intestinal obstruction or paralytic ileus.
Pregnancy & lactation, children under 12 years old.
Special Precautions
Should not be recommended when administering to hypotensive patients.
Side Effects
Nausea, headache, pruritus, rash, dizziness and hypotension or temporary lowering of blood pressure have been reported.
Allergic reactions, including anaphylaxis, have also occurred.
Drug Interactions
None known.
Caution For Usage
Note: Do not use the product if there are any significant changes in appearance of the capsules.
Storage
Store below 30°C in a dry place, away from direct sunlight.
Shelf life: Two years from manufacturing date.
ATC Classification
A03AX58 - alverine, combinations ; Belongs to the class of other drugs used for functional bowel disorders.
Presentation/Packing
Softgel cap 3 x 10's, 5 x 10's.
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in