Full Prescribing Info
Each mL contains travoprost 0.04 mg.
Pharmacology: Travoprost, a prostaglandin analogue is a selective FP prostanoid receptors agonist which reduces elevated intraocular pressure (IOP) by increasing uveoscleral outflow.
Raised intraocular pressure in open-angle glaucoma; ocular hypertension.
Dosage/Direction for Use
Instill once daily, preferably in the evening.
Special Precautions
Before initiating treatment, patients should be monitored for possible change in eye colour since an increase in the brown pigment in the iris may occur; particular care is required in those with mixed coloured irides and those receiving treatment to 1 eye only. Use with caution in patients with aphakia, pseudophakia with torn posterior lens capsule or anterior chamber lenses, and in those with known risk factors for cystoid macular oedema, iritis or uveitis. Care is also needed in patients with brittle or severe asthma.
Use with Other Contact Lenses: Contact lenses should be removed prior to instillation of Avatan and may be reinserted after 15 min of its administration.
Use with Other Ophthalmic Drugs: If >1 topical ophthalmic drugs is being used, Avatan should be administered at least 5 min between applications.
Use in pregnancy: Pregnancy Category C: Advised to avoid.
Use in lactation: Present in milk in animal studies; advised to avoid.
Use in children: Use in children <18 years is not recommended.
Use In Pregnancy & Lactation
Pregnancy: Pregnancy Category C: Advised to avoid.
Lactation: Present in milk in animal studies; advised to avoid.
Adverse Reactions
Adverse reactions of prostaglandin analogues and prostamides include brown pigmentation particularly in those with mixed-colour irides, blepharitis, ocular irritation and pain, conjunctival hyperaemia, transient punctate epithelial erosion, skin rash, dry eyes, headache and photophobia; they may also cause, darkening, thickening and lengthening of eye lashes. Less frequent adverse effects include eyelid oedema and rash, keratitis, blurred vision and conjunctivitis. There have been rare reports of dyspnoea, exacerbation of asthma, dizziness, arthralgia, myalgia, iritis. uveitis, local oedema, darkening of palpebral skin. Very rarely chest pain, palpitations and exacerbation of angina has also been reported. Also reported hypotension, bradycardia, browache.
Caution For Usage
Instructions for Use and Handling: To be dispensed only on or by the prescription of a registered physician.
Close the bottle immediately after use.
Discard 30 days after opening.
Store between 2°C and 25°C.
MIMS Class
Antiglaucoma Preparations
ATC Classification
S01EE04 - travoprost ; Belongs to the class of prostaglandin analogues. Used in the treatment of glaucoma.
Eye drops 0.004% w/v x 3 mL x 1's. 5 mL x 1's.
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