Clebopride


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult : PO Nausea and vomiting; Prokinetic agent 500 mcg 3 times/day. IV/IM Nausea and vomiting; As a prokinetic agent 0.5-1 mg.
Dosage Details
Oral
Nausea and vomiting, Prokinetic agent
Adult: As malate: 500 mcg tid.
Child: As malate: 15-20 mcg/kg tid.

Parenteral
Nausea and vomiting, Prokinetic agent
Adult: For acute symptoms: As malate: IV/IM: 0.5-1 mg.
Administration
Should be taken on an empty stomach. Take 30 min before meals.
Contraindications
GI haemorrhage, obstruction, perforation or immediately after surgery. Patients with pheochromocytoma.
Special Precautions
Impaired renal function, epilepsy, Parkinson's disease; history of depression. May impair ability to drive or operate machinery. Children, young patients, elderly.
Adverse Reactions
Extrapyramidal symptoms; restlessness, drowsiness, diarrhoea; hypotension, hypertension, dizziness, headache, depression; galactorrhoea.
Potentially Fatal: Neuroleptic malignant syndrome.
Drug Interactions
Other centrally active drugs and those with extrapyramidal effects. Increased toxicity with lithium. Antagonism of GI effects with antimuscarinics and opioid analgesics. May affect absorption of other drugs.
Lab Interference
Transient increased in plasma-aldosterone concentration.
Action
Description: Clebopride is a substituted benzamide with prokinetic and antiemetic properties.
Disclaimer: This information is independently developed by MIMS based on Clebopride from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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