Cravit

Cravit

levofloxacin

Manufacturer:

Daiichi-Sankyo

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Levofloxacin
Indications/Uses
Acute sinusitis; acute exacerbation of chronic bronchitis; community-acquired & nosocomial pneumonia; complicated & uncomplicated skin & skin structure infection (SSSI); complicated & uncomplicated UTI; chronic bacterial prostatitis; H. pylori infection; pyelonephritis including the acute type. Empiric treatment for community-acquired pneumonia.
Dosage/Direction for Use
Acute sinusitis 500 mg once daily for 10-14 days or 750 mg once daily for 5 days. Acute exacerbation of chronic bronchitis 500 mg once daily for 7 days or 750 mg once daily for 5 days. Community-acquired pneumonia 500 mg once daily for 7-14 days or 750 mg once daily for 5 days. Nosocomial pneumonia, complicated skin & skin structure infection (SSSI) 750 mg once daily for 7-14 days. Uncomplicated SSSI 500 mg once daily for 7-10 days. Uncomplicated UTI 250 mg once daily for 3 days. Complicated UTI 250 mg once daily for 10 days or 750 mg once daily for 5 days. Chronic bacterial prostatitis 500 mg once daily for 28 days. H. pylori infection 500 mg once daily for 10 days. Acute pyelonephritis 750 mg once daily for 5 days. Pyelonephritis 250 mg once daily for 10 days. Community-acquired pneumonia 500 mg once daily for 7-14 days or 750 mg once daily for 5 days.
Administration
May be taken with or without food: Take at least 2 hr before or after Fe salts, antacids & sucralfate. Ensure adequate fluid intake.
Contraindications
Hypersensitivity to ofloxacin or other quinolones. Epilepsy, history of tendon disorder related to fluoroquinolones. Childn/adolescents <16 yr. Pregnancy & lactation.
Special Precautions
Renal impairment, exposure to direct sunlight, known or suspected CNS disorder that may predispose to seizures or lower the seizure threshold, diabetes, serious heart disease, uncorrected electrolyte imbalance, receiving class 1A & III antiarrhythmic agents, myasthenia gravis. Discontinue use if pseudomembranous colitis occurs. Risk of tendonitis & tendon rupture in patient >60 yr, on concomitant corticosteroid & transplant recipients. May impair ability to drive or operate machinery.
Adverse Reactions
Sleep loss; dizziness, headache; nausea, vomiting, diarrhea, abdominal discomfort; increased AST, ALT, LDH & eosinophil count, decreased WBC count.
Drug Interactions
GI absorption interfered w/ Mg- & Al-containing antacids, sucralfate, metal cations & multivit prep w/ zinc. Pronounced lowering of the cerebral seizure threshold may occur w/ theophylline, fenbufen, phenylacetic acid or propionic acid derivatives. Hyperglycemia & hypoglycemia may occur w/ antidiabetic agents. Prolonged prothrombin time of warfarin. Prolonged QT may occur w/ quinidine sulfate, procainamide HCl, amiodarone HCl & sotalol HCl.
MIMS Class
Quinolones
ATC Classification
J01MA12 - levofloxacin ; Belongs to the class of fluoroquinolones. Used in the systemic treatment of infections.
Presentation/Packing
Form
Cravit FC tab 250 mg
Packing/Price
5's
Form
Cravit FC tab 500 mg
Packing/Price
5's
Form
Cravit FC tab 750 mg
Packing/Price
5's
Form
Cravit soln for infusion 5 mg/mL
Packing/Price
100 mL x 1's;150 mL x 1's;50 mL x 1's
/myanmar/image/info/cravit soln for infusion 5 mg-ml/5 mg-ml x 100 ml?id=6a67de21-1fa6-4461-9717-a8ff0100a63e
/myanmar/image/info/cravit soln for infusion 5 mg-ml/5 mg-ml x 150 ml?id=66e1cdf5-12c2-475c-805b-a8ff0100a63e
/myanmar/image/info/cravit soln for infusion 5 mg-ml/5 mg-ml  x 50 ml?id=d7d6b42f-efc9-429a-9e55-a8ff0100a63e
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