Adverse reactions which have been reported with the use of antihistamines are as follows: Central Nervous System:
Sedation and sleepiness (often transient), dizziness, disturbed coordination, confusion, restlessness, excitation, nervousness, tremor, irritability, insomnia, paresthesias, neuritis, convulsions, euphoria, hallucination and hysteria, drowsiness.
Dermatologic Effects (Integumentary):
Allergic manifestation of skin rash and edema, excessive perspiration, urticaria, photosensitivity.
Acute labyrinthitis, blurred vision, diplopia, vertigo, tinnitus.
Hypotension, palpitation, tachycardia and arrhythmias, extrasystoles, anaphylactic shock.
Hemolytic anemia, leukopenia, agranulocytosis, thrombocytopenia.
Cholestasis, hepatic failure, hepatitis, hepatic function abnormality, dryness of mouth, epigastric distress, anorexia, nausea, vomiting, diarrhoea, constipation, jaundice.
Urinary frequency, difficult urination, urinary retention, early menses.
Dryness of nose and throat, thickening of bronchial secretions, tightness of chest and wheezing, nasal stuffiness.
Fatigue, chills, headache, increased appetite/weight gain.