Those Indicating Need for Medical Attention:
Betamethasone: Less Frequent or Rare Incidence:
Allergic contact dermatitis (burning and itching of skin; apparent chronic therapeutic failure)- may also be caused by vehicle ingredients; folliculitis, furunculosis, pustules, pyoderma or vesiculation (painful, red or itchy, pus-containing blisters in hair follicles)- more frequent with occlusion or use of ointments in intertriginous areas; hyperesthesia (increased skin sensitivity); numbness in fingers; purpura (blood-containing blisters on skin); skin atrophy (thinning of skin with easy bruising, especially when used on facial or intertriginous area); skin infection, secondary- more frequent with occlusion; stripping of epidermal layer for tape dosage forms; telangiectasis (raises, dark red, wart-like spots on skin, especially when used on the face).
Rare Incidence: With prolonged use or other factors that increase absorption. Acneiform eruptions (acne or oily skin, especially when used on the face); cataracts, posterior subcapsular (gradual blurring or loss of vision)- reported with use of systemic corticosteroids; caution is advised with use of high- and very high-potency topical corticosteroids in periorbital area; Cushing's syndrome (backache; filling or rounding out of the face; irritability; menstrual irregularities; mental depressions; in men, unusual decrease in sexual desire or ability; unusual tiredness or weakness); dermatitis, perioral (irritation of skin around mouth); ecchymosis (unusual bruising); edema (increased blood pressure; rapid weight; swelling of feet or lower legs); gastric ulcer (loss of appetite; nausea; stomach bloating, burning, cramping, or pain; vomiting; weight loss); glaucoma, secondary (eye pain; gradual decrease in vision; nausea; vomiting)- with use of high- and very high-potency topical corticosteroids in peritoneal area; hirsutism or hypertrichosis (unusual increase in hair growth, especially on the face); hypertension; hypokalemia syndrome (irregular heartbeat; loss of appetite; muscle cramps or pain; nausea; severe weakness of extremities and trunk; vomiting); hypopigmentation (lightened skin color); or other changes in skin pigmentation; aggravation of infection; miliaria rubra (burning and itching of skin with pinhead-sized red blisters); protein depletion (muscle weakness); skin laceration (tearing of skin); skin maceration (softening of skin); striae (reddish purple lines on arms, face, legs, trunk, or groin); SC tissue atrophy; unusual loss of hair especially on the scalp.
Neomycin: More Frequent Incidence: Contact dermatitis (itching, rash, redness, swelling or other sign of skin irritation not present before therapy).
Rare Incidence: Ototoxicity (any loss of hearing).
Those Indicating Need for Medical Attention Only if They Continue or are Bothersome: Less Frequent or Rare Incidence:
Burning, dryness, irritation, itching or redness of skin, mild and transient; increased redness or scaling of skin lesions, mild and transient; skin rash, minor and transient.
Those Not Indicating Need for Medical Attention Only if They Continue or are Bothersome:
Stinging, mild and temporary, when foam, gel, lotion, solution or aerosol form of medication is applied.