Dioctahedral smectite


Concise Prescribing Info
Indications/Uses
Chronic diarrhoea.
Dosage/Direction for Use
Adult : PO 9 g/day for 7 days.
Dosage Details
Oral
Chronic diarrhoea
Adult: 9 g daily for 7 days.
Child: 2 years 3-6 g daily; >2 years 6-9 g daily. Treatment duration: Up to 7 days.
Reconstitution
Powder for oral susp: Stir thoroughly in half glass of water. For children, add 50 mL of water and stir thoroughly in the feeding bottle, or mix with a semi-liquid food (e.g. broth, stewed fruit, mashed vegetables, baby food).
Special Precautions
Intestinal occlusion. Children. Pregnancy and lactation.
Adverse Reactions
Gastrointestinal disorders: Rarely, aggravation of constipation.
Drug Interactions
May interfere with the absorption of other substances when administered simultaneously.
Action
Description: Dioctahedral smectite has a powerful coating property on the gastrointestinal mucosa. It protects the gastrointestinal mucosa by interacting with glycoprotein of mucus thus increasing the resistance of the mucosal gel as a response to aggressive agents.
Synonym: diosmectite.
Pharmacokinetics:
Absorption: Not absorbed.
Metabolism: Not metabolised.
Excretion: Via faeces.
Storage
Store below 25°C.
MIMS Class
ATC Classification
A07BC05 - diosmectite ; Belongs to the class of other intestinal adsorbents.
References
Buckingham R (ed). Smectites. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 03/04/2020.

Dehecta (Daewoong Pharmaceutical Co., Ltd). MIMS Philippines. http://www.mims.com/philippines. Accessed 03/04/2020.

Dehecta (Daewoong Pharmaceutical Co., Ltd). MIMS Thailand. http://www.mims.com/thailand. Accessed 07/04/2020.

Smecta (Beaufour Ipsen Industrie). MIMS Singapore. http://www.mims.com/singapore. Accessed 03/04/2020.

Smecta Orange-Vanilla (Beaufour Ipsen Industrie). MIMS Thailand. http://www.mims.com/thailand. Accessed 03/04/2020.

Smecta® (Dioctahedral Smectite): Not Recommended for Use in Children Aged Below 2 Years and Pregnant or Breastfeeding Women. National Pharmaceutical Regulatory Agency - Ministry of Health Malaysia. https://www.npra.gov.my/. Accessed 07/04/2020.

Disclaimer: This information is independently developed by MIMS based on Dioctahedral smectite from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
  • Smecta
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