Diprophylline


Concise Prescribing Info
Indications/Uses
Reversible airways obstruction.
Dosage/Direction for Use
Adult : PO 15 mg/kg 6 hrly.
Dosage Details
Oral
Reversible airways obstruction
Adult: 15 mg/kg every 6 hr.
Renal Impairment
Use with caution.
Administration
Should be taken on an empty stomach. Take 1 hr before or 1 hr after meals.
Contraindications
Hypersensitivity.
Special Precautions
Peptic ulceration, hyperthyroidism, hypertension, cardiac arrhythmias or other CV diseases, epilepsy, hepatic dysfunction, chronic alcoholism, acute febrile illness; smoking; neonates; elderly; pregnancy, lactation; impaired renal function.
Adverse Reactions
GI irritation and disturbances, CNS stimulation, headache, anxiety, restlessness, dizziness, tremor, palpitations.
Drug Interactions
Probenecid; xanthines (additive effects).
Action
Description: Diprophylline is a theophylline derivative which is used similarly to theophylline as a bronchodilator.
Pharmacokinetics:
Absorption: Rapidly absorbed from the GI tract.
Distribution: Distributed into breast milk.
Excretion: Mainly excreted unchanged in the urine. Elimination half-life: About 2 hr.
Disclaimer: This information is independently developed by MIMS based on Diprophylline from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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