Micro Labs


Zizawa Healthcare
Concise Prescribing Info
In conjunction w/ a mildly hypocaloric diet for the treatment of obese patients w/ BMI ≥30 kg/m2 or overwt patients (BMI ≥28 kg/m2) w/ associated risk factors.
Dosage/Direction for Use
Adult & childn ≥12 yr 120 mg tds.
Should be taken with food: Take immediately before, during or up to 1 hr after each main meal. If a meal is missed or contains no fat, the dose should be omitted.
Hypersensitivity. Chronic malabsorption syndrome; cholestasis. Lactation.
Special Precautions
Monitor antidiabetic medicinal product treatment. Do not coadminister w/ ciclosporin. There is a possibility of experiencing GI adverse reactions when taken w/ a diet high in fat. Cases of rectal bleeding have been reported. Monitor coagulation parameters in patients treated w/ concomitant oral anticoagulants. The use of additional contraceptive method is recommended to prevent possible failure of oral contraception that could occur in case of severe diarrhoea. The use of orlistat may be associated w/ hyperoxaluria & oxalate nephropathy in patients w/ underlying chronic kidney disease &/or vol depletion. Orlistat may unbalance anticonvulsant treatment by decreasing the absorption of antiepileptic drugs, leading to convulsions. Rare occurrence of hypothyroidism &/or reduced control of hypothyroidism. Pregnancy & lactation.
Adverse Reactions
Headache, upper & lower resp infection, abdominal pain/discomfort, oily spotting from the rectum, flatus w/ discharge, faecal urgency, fatty/oily stool, flatulence, liquid stools, oily evacuation, increased defecation, rectal pain, soft stools, faecal incontinence, abdominal distention, tooth disorder, gingival disorder, UTI, hypoglycaemia, influenza, fatigue, menstrual irregularity, anxiety.
Drug Interactions
Decreased ciclosporin & amiodarone plasma levels.
MIMS Class
Anti-Obesity Agents
ATC Classification
A08AB01 - orlistat ; Belongs to the class of peripherally acting antiobesity products.
Ecoslim cap 120 mg
4 × 21's
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