Generic Medicine Info
Indications and Dosage
Pain relief
Adult: Up to 1.2 g daily in divided doses.
Elderly: Reduced doses.
Porphyria, hypersensitivity, peptic ulceration, moderate/severe renal impairment.
Special Precautions
Patients with infection; haemorrhagic disorders; hypertension; cardiac function; asthma; diabetes mellitus; haemorrhoids; rectal irritation or bleeding; systemic lupus erythematosus; epilepsy, oedema; mental illness; parkinson's disease; polymyalgia rheumatica; temporal arthritis. Pregnancy and lactation. Monitor blood counts, kidney, liver and eye functions.
Adverse Reactions
GI disturbances; CNS effects; hypersensitivity reactions; blood disorders; nephrotoxicity; haematuria; oedema; pancreatitis; toxic epidermal necrolysis; alveolitis; Stevens-Johnson syndrome; photosensitivity; pulmonary eosinophilia.
Drug Interactions
Oral anticoagulants; antivirals; phenytoin; sulfonylurea antidiabetic; methotrexate; cardiac glycosides; ACE inhibitors; diuretics; β-blocker; other NSAIDs; lithium; ciclosporin; tacrolimus; moclobemide. Corticosteroids; antiplatelet drugs, biphosphonates, SSRIs and pentoxifylline increase GI bleeding risk. Avoid alcohol and tobacco.
Potentially Fatal: Increased risk of convulsions with quinolones.
Lab Interference
Thyroid function tests: Lowers serum thyroid hormone levels.
Description: It is an NSAID, which is an anthranilic acid derivative related to glafenine.
MIMS Class
Analgesics (Non-Opioid) & Antipyretics
Disclaimer: This information is independently developed by MIMS based on Floctafenine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by MIMS.com
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in