Floctafenine


Concise Prescribing Info
Indications/Uses
Pain relief.
Dosage/Direction for Use
Adult : PO Up to 1.2 g/day in divided doses.
Dosage Details
Oral
Pain relief
Adult: Up to 1.2 g daily in divided doses.
Elderly: Reduced doses.
Contraindications
Porphyria, hypersensitivity, peptic ulceration, moderate/severe renal impairment.
Special Precautions
Patients with infection; haemorrhagic disorders; hypertension; cardiac function; asthma; diabetes mellitus; haemorrhoids; rectal irritation or bleeding; systemic lupus erythematosus; epilepsy, oedema; mental illness; parkinson's disease; polymyalgia rheumatica; temporal arthritis. Pregnancy and lactation. Monitor blood counts, kidney, liver and eye functions.
Adverse Reactions
GI disturbances; CNS effects; hypersensitivity reactions; blood disorders; nephrotoxicity; haematuria; oedema; pancreatitis; toxic epidermal necrolysis; alveolitis; Stevens-Johnson syndrome; photosensitivity; pulmonary eosinophilia.
Drug Interactions
Oral anticoagulants; antivirals; phenytoin; sulfonylurea antidiabetic; methotrexate; cardiac glycosides; ACE inhibitors; diuretics; β-blocker; other NSAIDs; lithium; ciclosporin; tacrolimus; moclobemide. Corticosteroids; antiplatelet drugs, biphosphonates, SSRIs and pentoxifylline increase GI bleeding risk. Avoid alcohol and tobacco.
Potentially Fatal: Increased risk of convulsions with quinolones.
Lab Interference
Thyroid function tests: Lowers serum thyroid hormone levels.
Action
Description: It is an NSAID, which is an anthranilic acid derivative related to glafenine.
Disclaimer: This information is independently developed by MIMS based on Floctafenine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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