Flubendazole


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult : PO Enterobiasis 100 mg as a single dose. Repeat 2-3 wk later if needed. Ascariasis; Hookworm infections; Trichuriasis 100 mg twice daily for 3 days.
Dosage Details
Oral
Enterobiasis
Adult: 100 mg as a single dose. Repeat after 2-3 wk as required.
Child: Same as adult dose.

Oral
Ascariasis, Hookworm infections, Trichuriasis
Adult: 100 mg bid for 3 days.
Child: Same as adult dose.
Contraindications
Pregnancy.
Special Precautions
Lactation. Monitor blood counts and liver function tests regularly during treatment.
Adverse Reactions
GI disturbances; headache, dizziness; allergic reactions; raised liver enzyme values; alopoecia; bone marrow suppression.
Drug Interactions
Enzyme inducers eg phenytoin or carbamazepine; and inhibitors eg cimetidine.
Action
Description: Flubendazole inhibits cytoplasmic microtubules in the intestinal or absorptive cells of the worms, thus inhibiting glucose uptake and glycogen storage depletion, leading to death of the worms within days.
MIMS Class
Disclaimer: This information is independently developed by MIMS based on Flubendazole from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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