Zifam Pinnacle


Pinnacle House
Full Prescribing Info
Each capsule contains: Flucloxacillin Sodium BP equivalent to Flucloxacillin 250 mg or 500 mg.
Flucloxacillin sodium is C19H16ClFN3NaO5SH2O.
Excipients/Inactive Ingredients: q.s.
FLUCLOXA is a preparation of Flucloxacillin. It acts in similar way to penicillin by inhibiting bacterial cell wall synthesis.
Flucloxacillin is indicated for the treatment of infections due to gram-positive organisms, including infections caused by beta-lactamase producing Staphylococci.
Typical indications include: Respiratory tract infections: Pneumonia, lung abscess, empyema, sinusitis, pharyngitis, tonsillitis.
Skin and soft tissue infections: Boils, abscesses, carbuncles, furunculosis, infected skin conditions e.g. ulcer, eczema, acne, cellulitis, infected wounds, infected burns, etc.
Other infections caused by Flucloxacillin-sensitive organisms: Osteomyelitis, enteritis, endocarditis, urinary tract infection, meningitis, septicaemia.
Flucloxacillin is also indicated for use as a prophylactic agent during major surgical procedures where appropriate; for example, cardiothoracic and orthopedic surgery.
Dosage/Direction for Use
Doses should be administered half hour before meals.
Adult dosage (including elderly patients): 250 mg four times daily. Dose may be increased in severe infections.
In osteomyelitis, endocarditis: up to 8 g daily, in divided doses six to eight hourly.
Children's dosage: 2-10 years: half of adult dose; Under 2 years: one fourth of adult dose.
Problems of overdosage with Flucloxacillin are unlikely to occur. In case of overdosage patient should be treated symptomatically.
Flucloxacillin is contraindicated for those who have hypersensitivity to penicillins.
Use In Pregnancy & Lactation
Animal studies with Flucloxacillin have shown no teratogenic effects. The use of Flucloxacillin in pregnancy should be reserved for cases considered essential by the clinician.
Side Effects
Side effects, as with other penicillins, are uncommon and mainly of a mild and transitory nature. Gastrointestinal upsets (e.g. nausea, diarrhea) and skin rashes have been reported. If a skin rash occurs, treatment should be discontinued. Hepatitis and cholestatic jaundice have been rarely reported.
Store below 30°C and protect from moisture.
MIMS Class
ATC Classification
J01CF05 - flucloxacillin ; Belongs to the class of beta-lactamase resistant penicillins. Used in the systemic treatment of infections.
Cap 250 mg x 10 x 10's. 500 mg x 10 x 10's.
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