Flufenamic acid


Concise Prescribing Info
Indications/Uses
Pain and inflammation associated w/ musculoskeletal and joint disorders.
Dosage/Direction for Use
Adult : Topical As 3 or 3.5% preparation: Apply as directed.
Dosage Details
Topical/Cutaneous
Pain and inflammation associated with musculoskeletal and joint disorders
Adult: Apply as a topical preparation at 3% or 3.5%.
Contraindications
Hypersensitivity to aspirin or any other NSAIDs. Porphyria, active peptic ulceration.
Special Precautions
History of peptic ulceration. May mask signs of infection eg, fever. Patients with haemorrhagic disorders, hypertension, and impaired renal, hepatic, or cardiac function. Monitor for blood, kidney, liver, or eye disorders. Reduce dose in elderly.
Adverse Reactions
Photosensitivity, acute protocolitis, gastrointestinal discomfort, nausea, and diarrhoea
Potentially Fatal: Hypersensitivity and asthma.
Drug Interactions
May enhance the effects of oral anticoagulants, phenytoin and sulphonylureas. May increase plasma concentrations of lithium, methotrexate, and cardiac glycosides. Increased risk of hyperkalaemia with ACE inhibitors and potassium-sparing diuretics. May reduce antihypertensive action of some antihypertensives such as ACE inhibitors. May increase the risk of convulsions with quinolones.
Lab Interference
May lower serum-thyroid hormone levels.
Action
Description: Flufenamic acid is an NSAID which is an anthranilic acid derivative of mefenamic acid.
Disclaimer: This information is independently developed by MIMS based on Flufenamic acid from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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