Gallamine triethiodide


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult : IV Muscle relaxant in general anesth; Aid controlled ventilation Test dose may be given before anesth to determine drug sensitivity. Initial: 80-120 mg, further doses of 20-40 mg may be given as needed.
Dosage Details
Intravenous
Aid controlled ventilation, Muscle relaxant in general anaesthesia
Adult: Test dose: 20 mg may be given before anesth to determine drug sensitivity. Initially, 80-120 mg via IV inj, further doses of 20-40 mg may be given as required.
Child: 1.5 mg/kg. Neonates: 600 mcg/kg.
Contraindications
Severe renal impairment. Hypersensitivity to iodine. Mysasthenia gravis.
Special Precautions
Careful dose titration and monitoring of the degree of block are required to prevent overdosage.
Adverse Reactions
Tachycardia, increased BP.
Drug Interactions
Lidocaine, procainamide, quinidine, and verapamil may enhance the block. Clindamycin can prolong the action of muscle relaxants. Apnoea may be prolonged when used with polymyxins. Anticholinesterases or long-term treatment with corticosteroids may antagonise the action of gallamine.
Action
Description: Gallamine triethiodide is a benzylisoquinolinium competitive neuromuscular blocker. It is used to produce muscle relaxation in general anaesthesia during surgical procedures and to aid controlled ventilation.
Pharmacokinetics:
Distribution: Distributed throughout the body tissues after IV admin.
Metabolism: Not metabolised.
Excretion: Excreted as unchanged drug in the urine.
Disclaimer: This information is independently developed by MIMS based on Gallamine triethiodide from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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