Heparinoids


Concise Prescribing Info
Indications/Uses
Inflammation.
Dosage/Direction for Use
Adult : Topical As 0.3% w/w cream/gel: Apply 3-5 cm (or more, if necessary, up to 15 cm), as a thin layer, to affected area 2-4 times/day.
Dosage Details
Topical/Cutaneous
Inflammation
Adult: As 0.3% w/w cream/gel: Apply 3-5 cm (or more, if necessary, up to 15 cm), as a thin layer, to affected area 2-4 times daily.
Child: >5 yr As 0.3% w/w cream/gel: Same as adult dose.
Special Precautions
Childn.
Patient Counseling Information
Avoid contact on large areas of skin, broken or sensitive skin, or mucous membranes.
Action
Description: Heparinoid is a topical anticoagulant that has an anti-inflammatory effect by weakly inhibiting PGE2 synthesis and indirectly affecting LTB4 production. The thrombolytic effect is through potentiation of urokinase activity and the anti-exudatory effect is brought about by the inhibition of hyaluronidase.
Pharmacokinetics:
Excretion: Via urine, partly unchanged and depolymerised.
Storage
Store below 25°C.
ATC Classification
C05BA - Heparins or heparinoids for topical use ; Used in antivaricose therapy.
References
Buckingham R (ed). Heparinoids. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 13/06/2017.

Joint Formulary Committee. Heparinoid. British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 13/06/2017.

Disclaimer: This information is independently developed by MIMS based on Heparinoids from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in