Herbesser/Herbesser 60/Herbesser R100

Herbesser/Herbesser 60/Herbesser R100

diltiazem

Manufacturer:

Mitsubishi Tanabe

Distributor:

Toyota Tsusho
Concise Prescribing Info
Contents
Diltiazem HCl
Indications/Uses
Angina pectoris; variant angina pectoris. Essential HTN (mild to moderate).
Dosage/Direction for Use
Herbesser/Herbesser 60 Adult Angina pectoris, variant angina 30 mg tds, may be increased to 60 mg tds. Essential HTN (mild to moderate) 30-60 mg tds. Herbesser R 100 Adult Angina pectoris, variant angina 100 mg once daily. May be increased to 200 mg. Essential HTN (mild to moderate) 100-200 mg once daily.
Administration
Cap: May be taken with or without food: Swallow whole, do not chew/crush.|Tab: Should be taken on an empty stomach: Take before meals. Swallow whole, do not chew/crush.
Contraindications
History of hypersensitivity. CHF, 2nd- or 3rd-degree AV block, sick sinus syndrome, sinus arrest, or SA block. Pregnancy.
Special Precautions
Avoid abrupt w/drawal. CHF. Severe bradycardia (<50 beats/min), 1st degree AV block. Severe hypotension. Severe hepatic & renal dysfunction. May impair ability to drive or operate machinery. Concomitant use w/ other antiarrhythmic agents. Pregnancy & lactation. Childn & elderly.
Adverse Reactions
Stomach discomfort, constipation, abdominal pain; dizziness, bradycardia, facial hot flushes, AV block, hypersensitivity, headache; CHF; Stevens-Johnson syndrome, toxic epidermal necrolysis, exfoliative dermatitis.
Drug Interactions
Enhanced effects of antihypertensive agents, nitrates, dihydropyridine Ca antagonists, theophylline, triazolam, midazolam, muscle relaxants. Decreased effect w/ rifampicin. Increased adverse reactions w/ β-blockers, Rauwolfia prep, digitalis, antiarrhythmic drugs, aprindin HCl, cyclosporin, tacrolimus, carbamazepine, phenytoin, cimetidine, HIV protease inhibitors, anesth.
MIMS Class
Calcium Antagonists
ATC Classification
C08DB01 - diltiazem ; Belongs to the class of benzothiazepine derivative selective calcium-channel blockers with direct cardiac effects. Used in the treatment of cardiovascular diseases.
Presentation/Packing
Form
Herbesser R100 cap 100 mg
Packing/Price
10 × 10's
Form
Herbesser 60 tab 60 mg
Packing/Price
10 × 10's
Form
Herbesser tab 30 mg
Packing/Price
10 × 10's
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