Ibuproxam


Concise Prescribing Info
Indications/Uses
Pain and inflammation associated with musculoskeletal and joint disorders.
Dosage/Direction for Use
Adult : Topical As 5% oint: Apply 2-3 times/day for 4-5 days.
Dosage Details
Topical/Cutaneous
Pain and inflammation associated with musculoskeletal and joint disorders
Adult: As 5% ointment: Apply 2-3 times/day for 4-5 days.
Contraindications
Active peptic ulceration; hypersensitivity to aspirin and other NSAIDs.
Special Precautions
History of peptic ulceration; asthma; allergic disorders, coagulation defects; renal or hepatic impairment; history of cardiac failure, left ventricular dysfunction, hypertension or oedema due to other reasons; elderly, pregnancy and lactation.
Adverse Reactions
GI bleeding and discomfort, hypersensitivity reactions, headache.
Drug Interactions
Reduces effects of antihypertensives. Enhanced effect with moclobemide. Increased risk of GI bleeding with warfarin.
Potentially Fatal: Reduces antiplatelet effects of aspirin. Increases risk of methotrexate and lithium toxicity.
Action
Description: Ibuproxam is an NSAID. It inhibits prostaglandin synthesis.
Pharmacokinetics:
Absorption: Well absorbed orally. Peak plasma concentrations in about 45 min.
Metabolism: Partially metabolised to ibuprofen.
Excretion: Via urine (as metabolite and unchanged drug).
Disclaimer: This information is independently developed by MIMS based on Ibuproxam from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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