Indclav

Indclav Dosage/Direction for Use

amoxicillin + clavulanic acid

Manufacturer:

Indchemie Health Specialities

Distributor:

Royal Distribution

Marketer:

ESTI Pharma
Full Prescribing Info
Dosage/Direction for Use
Tablet: Usual dosages for the treatment of indication: Adults and children over 12 years: Mild to Moderate Infections: One INDCLAV* 625 tablet two times a day (bid). One tablet eight hourly (tid).
Severe Infections: One INDCLAV 1000 tablet two times a day (bid).
Therapy can be started parenterally and continued with an oral preparation.
Dosage in dental infections (e.g. dentoalveolar abscess): Adult and children over 12 years: One INDCLAV* 625 tablet two times a day for five days.
INDCLAV* 625 tablet and INDCLAV* 1000 tablets are not recommended in children 12 years and under.
Dosage in renal impairment: Adults: The INDCLAV* 1000 tablet should only be used in patients with a glomerular filtration rate of >30 ml/min.
Mild Impairment (Creatinine clearance >30 ml/min): No change in dosage (i.e. either one INDCLAV* 625 tablet bid or one INDCLAV 1000 tablet bid).
Moderate Impairment (Creatinine clearance 10 to 30 ml/min): One INDCLAV* 625 tablet bid. The INDCLAV* 1000 tablet should not be administered.
Severe impairment (Creatinine clearance <10 ml/min): Not more than one INDCLAV* 625 tablet every 24 hours.
Dosage in hepatic impairment: Dose with caution; monitor hepatic function at regular intervals.
Oral administration.
Tablets should be swallowed whole without chewing. If required, tablets may be broken in half, swallowed without chewing. To minimize potential gastrointestinal intolerance, administer at the start to a meal. The absorption of INDCLAV* optimized when taken at the start of a meal.
Treatment should not be extended beyond 14 days without review.
Syrup: The usual recommended daily dosage: Mild to moderate infections: 25/3.6 mg/kg/day e.g. recurrent tonsillitis, lower respiratory infections and skin and soft tissue infections; Serious infections: 45/6.4 mg/kg/day (upper respiratory tract infections e.g. otitis media and sinusitis, lower respiratory tract infections and skin and soft tissue infections). (See table.)

Click on icon to see table/diagram/image

Oral Administration.
To minimize potential gastrointestinal intolerance, administer at the start of a meal. The absorption of INDCLAV* Syrup is optimized when taken at the start of a meal. Therapy can be started parenterally and continued with an oral preparation.
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