Discontinue therapy if pain, visual field change, irritation, hyperemia occur or if ophthalmoxerosis is prolonged for >72 hr. Remove contact lenses prior to instillation; wait at least 30 min before reinsertion. Immediate measures should be taken in accidental oral dose. Do not use >30 days after opening. Do not allow the dropper tip to touch the eyes to prevent drug contamination. Do not use if soln becomes turbid.