Isoconazole + Diflucortolone


Concise Prescribing Info
Indications/Uses
Inflammatory skin fungal infections.
Dosage/Direction for Use
Adult : Topical Per g cream contains isoconazole nitrate 10 mg and diflucortolone valerate 1 mg: Apply twice daily.
Dosage Details
Topical/Cutaneous
Inflammatory skin fungal infections
Adult: Each g of cream contains isoconazole nitrate 10 mg and diflucortolone valerate 1 mg. Apply to the affected area bid. Once inflammation has subsided, treatment should be continued with isoconazole cream (without the steroid component).
Contraindications
Tuberculous and syphilitic infections in the area to be treated, viral infections (herpes simplex, vaccinia, varicella and smallpox). Pregnancy.
Special Precautions
Not to be used on skin creases due to presence of potent corticosteroid. Prolonged use may lead to skin thinning, loss of elasticity, dilatation of superficial blood vessels, telangiectasiae and ecchymoses especially when used on face or with occlusive dressings. Excessive use on damaged skin may lead to substantial systemic absorption resulting in depression of the hypothalmus-pituitary adrenal axis especially in children. Caution when used near the eye. Not recommended for use in infants and children.
Adverse Reactions
Local reactions such as burning and itching.
Action
Description: Isoconazole nitrate is an imidazole antifungal that is used in the treatment of superficial skin fungal infections. It is effective against dermatophytes and yeasts, yeast-like fungi and moulds. Diflucortolone valerate is a corticosteroid that suppresses inflammation in inflammatory and allergic skin conditions; it also relieves itching, burning and pain. They are used together for the treatment of inflammatory or eczematous skin fungal infections.
Storage
Store below 25°C.
Disclaimer: This information is independently developed by MIMS based on Isoconazole + Diflucortolone from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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